Evidence map›Paper›PMID 30482093›Full record

ArticleLupus2019

Relationships among organ damage, social support, and depression in African American women with systemic lupus erythematosus.

J Jordan, N J Thompson, C Dunlop-Thomas, S Sam Lim, C Drenkard

Abstract read
In one paragraph

Article in Lupus, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

J Jordan1 Rollins School of Public Health, Atlanta, GA, United States.
N J Thompson1 Rollins School of Public Health, Atlanta, GA, United States.
C Dunlop-Thomas2 School of Medicine, Emory University, Atlanta, GA, United States.
S Sam Lim2 School of Medicine, Emory University, Atlanta, GA, United States.
C Drenkard2 School of Medicine, Emory University, Atlanta, GA, United States.ORCID https://orcid.org/0000-0002-6832-7291

Funding

The Georgians Organized Against Lupus (GOAL) Cohort: Advancing Health DisparitiesU01DP005119 · DP · EMORY UNIVERSITY · PI DRENKARD, CRISTINA MARTA, LIM, SUNG SAM · 2014 to 2018
$4.8M
ACL HHS U01DP005119NCCDPHP CDC HHS U01 DP005119NCCDPHP CDC HHS U01 DP006488
6 · The paper itself

Abstract

objectivesSystemic lupus erythematosus (SLE) disproportionately strikes African American women. Social support can potentially reduce disease impact. The purpose of this study is to understand the relationship between organ damage and depression in African American women and how social support influences this relationship.

methodsWe used a mixed methods design, analyzing self-reported data on lupus-related organ damage, depression, and social support in 437 African American women with SLE recruited in the Georgians Organized Against Lupus (GOAL) cohort. Moreover, we conducted interviews among 15 GOAL participants to gather patients' perspectives about the role of social support in people who live with lupus.

resultsWe found a significant association between organ damage and depression ( r = 0.163, p = 0.001), as well as between depression and social support ( F = 17.574, p < 0.001). The quantitative analysis did not render social support as a significant moderator in the organ damage-depression relationship. Interviews, however, revealed that African American women with the most severe organ damage have the greatest need for support.

conclusionsSocial support is a key resource for lupus patients with high disease burden. Overall, these findings highlight the importance of monitoring depressive symptoms in this population and developing interventions aimed to increase social support available to lupus patients.

Indexed as

Social SupportAdultBlack or African AmericanCohort StudiesDepressionFemaleGeorgiaHumansInterviews as TopicLinear ModelsLupus Erythematosus, SystemicMiddle AgedPsychiatric Status Rating ScalesSelf ReportSeverity of Illness IndexAfrican Americandepressionlupusorgan damagesocial supportsystemic lupus erythematosus

Identifiers

PMID30482093
PMCPMC6415670

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.