Evidence map›Paper›PMID 30482040›Full record

ReviewExperimental biology and medicine (Maywood, N.J.)2018

Functional optical coherence tomography of retinal photoreceptors.

Xincheng Yao, Taeyoon Son, Tae-Hoon Kim, Yiming Lu

Open access · bronzeAbstract readReview
In one paragraph

Review in Experimental biology and medicine (Maywood, N.J.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Emerging imaging developments in experimental vision sciences and ophthalmology.Experimental biology and medicine (Maywood, N.J.) · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Functional optical coherence tomography enablesBiomedical optics express · 2020
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Xincheng Yao1 Department of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
Taeyoon Son1 Department of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
Tae-Hoon Kim1 Department of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
Yiming Lu1 Department of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
University of Illinois Chicago · US

Funding

Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MCANANY, JAMES JASON · 1985 to 2025
$14.8M
Functional imaging of retinal photoreceptorsR01EY023522 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI YAO, XINCHENG · 2014 to 2024
$3.5M
Super-resolution ophthalmoscopy for in vivo retinal imagingR01EY024628 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI YAO, XINCHENG · 2014 to 2016
$1.1M
NEI NIH HHS P30 EY001792NEI NIH HHS R01 EY023522NEI NIH HHS R01 EY024628
6 · The paper itself

Abstract

impact statementRetinal photoreceptors are the primary target of age-related macular degeneration (AMD) which is the leading cause of severe vision loss and legal blindness. An objective method for functional assessment of photoreceptor physiology can benefit early detection and better treatment evaluation of AMD and other eye diseases that are known to cause photoreceptor dysfunctions. This article summarizes in vitro study of IOS mechanisms and in vivo demonstration of IOS imaging of intact animals. Further development of the functional IOS imaging may provide a revolutionary solution to achieve objective assessment of human photoreceptors.

Indexed as

Photoreceptor Cells, VertebrateAnimalsHumansMacular DegenerationTomography, Optical Coherenceage-related macular degenerationintrinsic optical signalOptical coherence tomographyphotoreceptors

Identifiers

PMID30482040
PMCPMC6348599
OpenAlexW2902340184

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.