Evidence map›Paper›PMID 30481876›Full record

ReviewZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology2018

[Advances in research on cell fate determinant Numb regulating liver cancer].

X R Yang, J Sun, J Wang, Y Y Lu

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

X R YangComprehensive Liver Cancer Center, 302 Military Hospital of Chinese Army, Beijing 100039, China.
J SunComprehensive Liver Cancer Center, 302 Military Hospital of Chinese Army, Beijing 100039, China.
J WangBeijing Institute of Basic Medical Sciences, Beijing 100850, China.
Y Y LuComprehensive Liver Cancer Center, 302 Military Hospital of Chinese Army, Beijing 100039, China.
Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences

Funding

National Natural Science Foundation of China 81470865, 81672368, 81672467Natural Science Foundation of Beijing 5162026, 7172207
6 · The paper itself

Abstract

Liver cancer is one of the most common malignant tumors in China, ranking fifth in malignant tumors and the third in tumor-related deaths. As a membrane-related protein, the asymmetric distribution of cell fate determinant Numb plays a key role in cell differentiation. Research reports that Numb may be closely associated to the occurrence and development of tumors. Recently, scholars have gradually valued its important role in liver cancer. This article briefly reviews the structure of Numb molecule, relationship between Numb and tumorigenesis, the molecular mechanism of Numb-regulated tumors, and the role of Numb in the development of liver cancer.

Indexed as

Cell DifferentiationLiver NeoplasmsMembrane ProteinsAdultChinaHumansMembrane ProteinsCell fate determinantLiver neoplasmsNumb

Identifiers

PMID30481876
PMCPMC12769052
OpenAlexW3025501779

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.