Evidence map›Paper›PMID 30481728›Full record

ArticleRedox biology2019

Stable integration of the Mrx1-roGFP2 biosensor to monitor dynamic changes of the mycothiol redox potential in Corynebacterium glutamicum.

Quach Ngoc Tung, Vu Van Loi, Tobias Busche, Andreas Nerlich, Maren Mieth, Johanna Milse, Jörn Kalinowski, Andreas C Hocke, Haike Antelmann

Open access · goldAbstract read
In one paragraph

Article in Redox biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. In Vivo Imaging with Genetically Encoded Redox Biosensors.International journal of molecular sciences · 2020
    Review
  5. Single-Base Genome Editing inJournal of microbiology and biotechnology · 2020
    Article
  6. The Industrial OrganismAntioxidants (Basel, Switzerland) · 2020
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Frontiers in microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Quach Ngoc TungFreie Universität Berlin, Institute for Biology-Microbiology, D-14195 Berlin, Germany.
Vu Van LoiFreie Universität Berlin, Institute for Biology-Microbiology, D-14195 Berlin, Germany.
Tobias BuscheFreie Universität Berlin, Institute for Biology-Microbiology, D-14195 Berlin, Germany; Center for Biotechnology (CeBiTec), Universitätsstraße 25, D-33615 Bielefeld, Germany.
Andreas NerlichDepartment of Internal Medicine/Infectious Diseases and Respiratory Medicine, Charité -Universitätsmedizin Berlin, D-10117 Berlin, Germany.
Maren MiethDepartment of Internal Medicine/Infectious Diseases and Respiratory Medicine, Charité -Universitätsmedizin Berlin, D-10117 Berlin, Germany.
Johanna MilseCenter for Biotechnology (CeBiTec), Universitätsstraße 25, D-33615 Bielefeld, Germany.
Jörn KalinowskiCenter for Biotechnology (CeBiTec), Universitätsstraße 25, D-33615 Bielefeld, Germany.
Andreas C HockeDepartment of Internal Medicine/Infectious Diseases and Respiratory Medicine, Charité -Universitätsmedizin Berlin, D-10117 Berlin, Germany.
Haike AntelmannFreie Universität Berlin, Institute for Biology-Microbiology, D-14195 Berlin, Germany. Electronic address: haike.antelmann@fu-berlin.de.
Bielefeld University · DECharité - Universitätsmedizin Berlin · DEFreie Universität Berlin · DE

Funding

European Research Council 615585
6 · The paper itself

Abstract

Mycothiol (MSH) functions as major low molecular weight (LMW) thiol in the industrially important Corynebacterium glutamicum. In this study, we genomically integrated an Mrx1-roGFP2 biosensor in C. glutamicum to measure dynamic changes of the MSH redox potential (E

Indexed as

Biosensing TechniquesGene ExpressionGenes, ReporterOxidation-ReductionAmino Acid SequenceBacterial ProteinsCorynebacterium glutamicumGreen Fluorescent ProteinsHydrogen PeroxideIntracellular SpaceModels, BiologicalModels, MolecularMutationOxidative StressProtein ConformationReactive Oxygen SpeciesBacterial ProteinsGreen Fluorescent ProteinsHydrogen PeroxideReactive Oxygen SpeciesRecombinant Fusion ProteinsCorynebacterium glutamicumMrx1-roGFP2MycothiolMycothiol redox potential

Identifiers

PMID30481728
PMCPMC6258114
OpenAlexW2901952657

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.