ArticleWorld neurosurgery2019
Clinical Evaluation of Shot-Within-Shot Optimization for Gamma Knife Radiosurgery Planning and Delivery.
Article in World neurosurgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Stereotactic radiosurgery for multiple small brain metastases using gamma knife versus single-isocenter VMAT: Normal brain dose based on lesion number and size.Journal of applied clinical medical physics · 2025Article
- Evaluating the impact of prescription isodose line on plan quality using Gamma Knife inverse planning.Journal of applied clinical medical physics · 2021Article
- Associating dose-volume characteristics with theoretical radiobiological metrics for rapid Gamma Knife stereotactic radiosurgery plan evaluation.Journal of applied clinical medical physics · 2020Article
- Data for optimizing Gamma Knife radiosurgery using the shot within shot technique.Data in brief · 2019Article
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6 authors.
Funding
Abstract
objectiveShot-within-shot (SWS) optimization is a new planning technique that relies on various combinations of shot weighting and prescription isodose line (IDL) to reduce beam-on time. The method differs from other planning techniques that incorporate mixed collimation, multiple stereotactic coordinates, and traditionally low prescription IDLs (<60%). In this work, we evaluate the percentage of brain metastasis for which the method can be applied, the magnitude of the resultant time savings, and the possible tradeoffs in plan quality.
methodsA retrospective analysis was performed on 75 patients treated for 241 metastatic lesions in the brain. For each lesion, the original planning metrics related to target coverage, conformity, gradient, and beam-on time were recorded. A subset of lesions were selected for replanning using the SWS technique based on size, shape, and proximity to critical structures. Two replans were done, a reference plan was prescribed at the 50% IDL, and an optimized plan was prescribed at an IDL typically >50%. Planning metrics were then compared among the original plan and the 2 replans.
resultsMore than a third (39%) of the brain metastases were eligible for the SWS technique. For these lesions, the differences between the original plan and reference SWS plan were as follows: ΔV
conclusionsThis work demonstrates clinically that optimization using the shot-within-shot technique can reduce beam-on time without degrading treatment plan quality.
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