ArticleJournal of experimental botany2019
PERPETUAL FLOWERING2 coordinates the vernalization response and perennial flowering in Arabis alpina.
Article in Journal of experimental botany, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 21 citations in OpenAlex.
- Integrative multi-omics analyses reveal transcriptional, metabolic, and hormonal regulation of vernalization-induced flowering in Wucai (Brassica rapa).Molecular horticulture · 2026Article
- Transcriptome Profiling Reveals Key Regulatory Networks for Age-Dependent Vernalization in Welsh Onion (International journal of molecular sciences · 2024Article
- Flowering genes identification, network analysis, and database construction for 837 plants.Horticulture research · 2024Article
- The central role of stem cells in determining plant longevity variation.Plant communications · 2023Review
- Genome-wide association study of 23 flowering phenology traits and 4 floral agronomic traits in tree peony (Horticulture research · 2023Article
- MiR172-APETALA2-like genes integrate vernalization and plant age to control flowering time in wheat.PLoS genetics · 2022Article
- Arabis alpina: A perennial model plant for ecological genomics and life-history evolution.Molecular ecology resources · 2022Review
- The Diverse Roles of FLOWERING LOCUS C in Annual and Perennial Brassicaceae Species.Frontiers in plant science · 2021Review
- Plant Inflorescence Architecture: The Formation, Activity, and Fate of Axillary Meristems.Cold Spring Harbor perspectives in biology · 2020Review
- Gibberellins Act Downstream ofPlant physiology · 2019Article
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8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The floral repressor APETALA2 (AP2) in Arabidopsis regulates flowering through the age pathway. The AP2 ortholog in the alpine perennial Arabis alpina, PERPETUAL FLOWERING 2 (PEP2), was previously reported to control flowering through the vernalization pathway via enhancing the expression of another floral repressor PERPETUAL FLOWERING 1 (PEP1), the ortholog of Arabidopsis FLOWERING LOCUS C (FLC). However, PEP2 also regulates flowering independently of PEP1. To characterize the function of PEP2, we analyzed the transcriptomes of pep2 and pep1 mutants. The majority of differentially expressed genes were detected between pep2 and the wild type or between pep2 and pep1, highlighting the importance of the PEP2 role that is independent of PEP1. Here, we demonstrate that PEP2 activity prevents the up-regulation of the A. alpina floral meristem identity genes FRUITFUL (AaFUL), LEAFY (AaLFY), and APETALA1 (AaAP1), ensuring floral commitment during vernalization. Young pep2 seedlings respond to vernalization, suggesting that PEP2 regulates the age-dependent response to vernalization independently of PEP1. The major role of PEP2 through the PEP1-dependent pathway takes place after vernalization, when it facilitates PEP1 activation both in the main shoot apex and in axillary branches. These multiple roles of PEP2 in the vernalization response contribute to the A. alpina life cycle.
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