ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2019
Prevalence and Determinants of QuantiFERON-Diagnosed Tuberculosis Infection in 9810 Mongolian Schoolchildren.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 40 citations in OpenAlex.
- Influence of vitamin D supplementation on bone mineral content, bone turnover markers, and fracture risk in South African schoolchildren: multicenter double-blind randomized placebo-controlled trial (ViDiKids).Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024Trial
- Influence of vitamin D supplementation on growth, body composition, pubertal development and spirometry in South African schoolchildren: a randomised controlled trial (ViDiKids).BMJ paediatrics open · 2024Trial
- Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease.The New England journal of medicine · 2020Trial
- Differential Effects of Oral Boluses of Vitamin D2 vs Vitamin D3 on Vitamin D Metabolism: A Randomized Controlled Trial.The Journal of clinical endocrinology and metabolism · 2019Trial
- Incidence and determinants of fracture risk in 8,348 Mongolian schoolchildren: secondary analysis of data from a randomised controlled trial.medRxiv : the preprint server for health sciences · 2025Article
- Vitamin D Status, Fasting Blood Glucose, and Latent Tuberculosis Infection in a High-Risk Population in Ulaanbaatar, Mongolia.Nutrients · 2025Article
- Prevalence, incidence and determinants of QuantiFERONIJTLD open · 2024Article
- Smoking Exposure and the Risk of Latent Tuberculosis Infection: Results from NHANES 2011-2012.Toxics · 2024Article
- Influence of vitamin D supplementation on muscle strength and exercise capacity in South African schoolchildren: secondary outcomes from a randomised controlled trial (ViDiKids).BMJ open sport & exercise medicine · 2024Article
- Association of Single-Nucleotide Polymorphisms in theInfection and drug resistance · 2023Article
- Integrated Spreadsheets for Nutritional Analysis of Population Diet Surveys.Journal of visualized experiments : JoVE · 2022Article
- Tobacco Smoking and Second-Hand Smoke Exposure Impact on Tuberculosis in Children.Journal of clinical medicine · 2022Article
- Prevalence and Determinants of Vitamin D Deficiency in 1825 Cape Town Primary Schoolchildren: A Cross-Sectional Study.Nutrients · 2022Article
- Serial T-SPOT.TB responses in Tanzanian adolescents: Transient, persistent and irregular conversions.PloS one · 2022Article
- Indoor Air Pollution and Susceptibility to Tuberculosis Infection in Urban Vietnamese Children.American journal of respiratory and critical care medicine · 2021Article
- Article
- Implementing contact tracing for tuberculosis in Kyrgyz Republic and risk factors for positivity using QuantiFERON-TB Gold plus.BMC infectious diseases · 2020Article
- Consensus statement from 2Reviews in endocrine & metabolic disorders · 2020Article
- The association between vitamin D status and infectious diseases of the respiratory system in infancy and childhood.Hormones (Athens, Greece) · 2019Review
- Risk factors for active tuberculosis in 938 QuantiFERON-positive schoolchildren in Mongolia: a community-based cross-sectional study.BMC infectious diseases · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 6 institutions in 4 countries.
Funding
Abstract
backgroundThere is controversy regarding the potential influence of vitamin D deficiency, exposure to environmental tobacco smoke, BCG vaccination, season, and body habitus on susceptibility to Mycobacterium tuberculosis (MTB) infection.
methodsWe conducted a cross-sectional analysis to identify determinants of a positive QuantiFERON-TB Gold (QFT) assay result in children aged 6-13 years attending 18 schools in Ulaanbaatar, Mongolia. Data relating to potential risk factors for MTB infection were collected by questionnaire, physical examination, and determination of serum 25-hydroxyvitamin D (25[OH]D) concentrations. Risk ratios (RRs) were calculated with adjustment for potential confounders, and population attributable fractions (PAFs) were calculated for modifiable risk factors identified.
resultsNine hundred forty-six of 9810 (9.6%) participants had a positive QFT result. QFT positivity was independently associated with household exposure to pulmonary tuberculosis (adjusted RR [aRR], 4.75 [95% confidence interval {CI}, 4.13-5.46, P < .001]; PAF, 13.1% [95% CI, 11.1%-15.0%]), vitamin D deficiency (aRR, 1.23 [95% CI, 1.08-1.40], P = .002; PAF, 5.7% [95% CI, 1.9%-9.3%]), exposure to environmental tobacco smoke (1 indoor smoker, aRR, 1.19 [95% CI, 1.04-1.35]; ≥2 indoor smokers, aRR, 1.30 [95% CI, 1.02-1.64]; P for trend = .006; PAF, 7.2% [95% CI, 2.2%-12.0%]), and increasing age (aRR per additional year, 1.14 [95% CI, 1.10-1.19], P < .001). No statistically significant independent association was seen for presence of a BCG scar, season of sampling, or body mass index.
conclusionsVitamin D deficiency and exposure to environmental tobacco smoke are potentially modifiable risk factors for MTB infection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.