Evidence map›Paper›PMID 30481161›Full record

ArticleAging2018

Transcriptional expressions of Chromobox 1/2/3/6/8 as independent indicators for survivals in hepatocellular carcinoma patients.

Gang Ning, Yan-Lin Huang, Li-Min Zhen, Wen-Xiong Xu, Qian Jiao, Fang-Ji Yang, Li-Na Wu, Yong-Yuan Zheng, Jie Song, Yen-Sheng Wang and 2 more

Open access · greenAbstract read
In one paragraph

Article in Aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Gang Ning *Department of Infectious Diseases, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Yan-Lin Huang *Department of Infectious Diseases, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Li-Min Zhen *Department of Infectious Diseases, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Wen-Xiong XuDepartment of Infectious Diseases, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Qian JiaoDepartment of Infectious Diseases, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Fang-Ji YangDepartment of Infectious Diseases, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Li-Na WuDepartment of Infectious Diseases, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Yong-Yuan ZhengDepartment of Infectious Diseases, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Jie SongDepartment of Infectious Diseases, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Yen-Sheng WangDepartment of Environmental Health Science, Yale School of Public Health, New Haven, Connecticut 06520, USA.
Chan XieDepartment of Infectious Diseases, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Liang PengDepartment of Infectious Diseases, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Third Affiliated Hospital of Sun Yat-sen University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chromobox (CBX) proteins are important components of epigenetic regulation complexes known to play key roles in hepatocellular carcinoma (HCC). Little is known about the function of distinct CBXs in HCC. To address this issue, the study investigated the roles of CBXs in the prognosis of HCC using ONCOMINE, UALCAN, Human Protein Atlas, Kaplan-Meier Plotter,

Indexed as

AgedCarcinoma, HepatocellularChromobox Protein Homolog 5Epigenesis, GeneticFemaleGene Expression Regulation, NeoplasticHumansLiver NeoplasmsMaleMiddle AgedMultigene FamilyMutationPolycomb-Group ProteinsRNA, MessengerCBX1 protein, humanChromobox Protein Homolog 5Polycomb-Group ProteinsRNA, MessengerCBXhepatocellular carcinomaKaplan-Meier plotterONCOMINEprognosis

Identifiers

PMID30481161
PMCPMC6286817
OpenAlexW2903265189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.