Evidence map›Paper›PMID 30480858›Full record

ArticleJournal of leukocyte biology2018

Buprenorphine: Therapeutic potential beyond substance abuse.

Stephani Velasquez, Jay Rappaport

Open access · greenAbstract readEditorialComment
In one paragraph

Article in Journal of leukocyte biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Stephani VelasquezDepartment of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers University, The State University of New Jersey, USA.
Jay RappaportTulane National Primate Research Center, Tulane University, Health Sciences Center, Covington, Louisiana, USA.
Rutgers, The State University of New Jersey · USTulane University · US

Funding

TRAINING PROGRAM: DRUGS OF ABUSE RELATED NEUROPEPTIDEST32DA007237 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI ELLEN M UNTERWALD · 1988 to 2026
$10.6M
Project 3: Targeting Neurokinin 1 ReceptorP01MH105303 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI LEWIS, MARK G. · 2014 to 2017
$4.3M
NIDA NIH HHS T32 DA007237NIDA-supported Ruth L. Kirschstein training T32 DA007237NIMH NIH HHS P01 MH105303NIMH NIH HHS P01MH105303
6 · The paper itself

Abstract

Discussion of buprenorphine and its potential utility for the treatment of inflammatory disorders.

Indexed as

BuprenorphineSubstance-Related DisordersChemokine CCL2HumansMonocytesBuprenorphineCCL2 protein, humanChemokine CCL2immune activationinflammationmonocyteopioidstransmigration

Identifiers

PMID30480858
PMCPMC6476568
OpenAlexW2902359780

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.