Evidence map›Paper›PMID 30480828›Full record

ArticleCancer2019

Trends in liver cancer mortality in the United States: Dual burden among foreign- and US-born persons.

Meheret Endeshaw, Benjamin D Hallowell, Hilda Razzaghi, Virginia Senkomago, Matthew T McKenna, Mona Saraiya

Abstract readComparative Study
In one paragraph

Article in Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 43 citations in OpenAlex.

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  6. Access to care and the Hispanic paradox among Hispanic patients with hepatocellular carcinoma.Clinics and research in hepatology and gastroenterology · 2025
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  19. Serum Biomarkers of Iron Status and Risk of Hepatocellular Carcinoma Development in Patients with Nonalcoholic Fatty Liver Disease.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Meheret EndeshawCenters for Disease Control and Prevention, Atlanta, Georgia.
Benjamin D HallowellCenters for Disease Control and Prevention, Atlanta, Georgia.
Hilda RazzaghiCenters for Disease Control and Prevention, Atlanta, Georgia.ORCID 0000-0002-8053-9748
Virginia SenkomagoCenters for Disease Control and Prevention, Atlanta, Georgia.
Matthew T McKennaEmory University School of Medicine, Atlanta, Georgia.
Mona SaraiyaCenters for Disease Control and Prevention, Atlanta, Georgia.ORCID 0000-0002-4527-828X
Centers for Disease Control and Prevention · USEmory University · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundSince the mid-1980s, the burden of liver cancer in the United States has doubled, with 31,411 new cases and 24,698 deaths occurring in 2014. Foreign-born individuals may be more likely to die of liver cancer than individuals in the general US-born population because of higher rates of hepatitis B infection, a low socioeconomic position, and language barriers that limit the receipt of early cancer detection and effective treatment.

methodsTo determine whether liver cancer mortality rates were higher among foreign-born individuals versus US-born individuals in the United States, population-based cancer mortality data were obtained from the National Center for Health Statistics of the Centers for Disease Control and Prevention. Annual population estimates were obtained from the US Census Bureau's American Community Survey. Age-adjusted mortality rates and rate ratios (RRs) for liver cancer stratified by birth place were calculated, and the average annual percent change (AAPC) was used to evaluate trends.

resultsA total of 198,557 deaths from liver and intrahepatic bile duct cancer were recorded during 2005-2014, and 16% occurred among foreign-born individuals. Overall, foreign-born individuals had a 24% higher risk of liver cancer mortality than US-born individuals (RR, 1.24; 95% confidence interval [CI], 1.22-1.25). Foreign-born individuals did not have any significant changes in liver cancer mortality rates overall, but among US-born individuals, liver cancer mortality rates significantly increased (AAPC, 2.7; 95% CI, 2.1-3.3).

conclusionsEfforts that address the major risk factors for liver cancer are needed to help to alleviate the health disparities observed among foreign-born individuals and reverse the increasing trend observed in the US-born population.

Indexed as

AdultAgedAged, 80 and overEmigrants and ImmigrantsFemaleHumansLiver NeoplasmsMaleMiddle AgedMortalityNational Center for Health Statistics, U.S.Residence CharacteristicsUnited Statescancerforeign-bornhepatitis Bhepatitis Cliverliver and intrahepatic bile ductliver cancermortalitymortality ratesnativity statusUS-born

Identifiers

PMID30480828
PMCPMC6681907
OpenAlexW2903151324

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.