Evidence map›Paper›PMID 30480666›Full record

ArticleScientific data2018

Columbia Open Health Data, clinical concept prevalence and co-occurrence from electronic health records.

Casey N Ta, Michel Dumontier, George Hripcsak, Nicholas P Tatonetti, Chunhua Weng

Abstract readDataset
In one paragraph

Article in Scientific data, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Identifying Phenotypes for Earlier Diagnosis of Rare Diseases.Studies in health technology and informatics · 2025
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  12. Big Data in Nephrology.Nature reviews. Nephrology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Casey N TaDepartment of Biomedical Informatics, Columbia University, NY, USA.
Michel DumontierInstitute of Data Science, Maastricht University, Maastricht, The Netherlands.ORCID 0000-0003-4727-9435
George HripcsakDepartment of Biomedical Informatics, Columbia University, NY, USA.
Nicholas P TatonettiDepartment of Biomedical Informatics, Columbia University, NY, USA.
Chunhua WengDepartment of Biomedical Informatics, Columbia University, NY, USA.

Funding

DISCOVERING AND APPLYING KNOWLEDGE IN CLINICAL DATABASESR01LM006910 · NLM · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HRIPCSAK, GEORGE M · 2000 to 2023
$10.6M
Bridging the Semantic Gap Between Research Eligibility Criteria and Clinical DataR01LM009886 · NLM · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WENG, CHUNHUA · 2009 to 2020
$5.3M
Biomedical Data Translator Technical Feasibility Assessment and Architecture DesignOT3TR002027 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DUMONTIER, MICHEL, TATONETTI, NICHOLAS P · 2016 to 2019
$2.7M
Drug Effect Discovery Through Data Mining and Integrative Chemical BiologyR01GM107145 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI TATONETTI, NICHOLAS P · 2014 to 2018
$2.5M
NCATS NIH HHS OT3 TR002027NIGMS NIH HHS R01 GM107145NLM NIH HHS R01 LM006910NLM NIH HHS R01 LM009886
6 · The paper itself

Abstract

Columbia Open Health Data (COHD) is a publicly accessible database of electronic health record (EHR) prevalence and co-occurrence frequencies between conditions, drugs, procedures, and demographics. COHD was derived from Columbia University Irving Medical Center's Observational Health Data Sciences and Informatics (OHDSI) database. The lifetime dataset, derived from all records, contains 36,578 single concepts (11,952 conditions, 12,334 drugs, and 10,816 procedures) and 32,788,901 concept pairs from 5,364,781 patients. The 5-year dataset, derived from records from 2013-2017, contains 29,964 single concepts (10,159 conditions, 10,264 drugs, and 8,270 procedures) and 15,927,195 concept pairs from 1,790,431 patients. Exclusion of rare concepts (count ≤ 10) and Poisson randomization enable data sharing by eliminating risks to patient privacy. EHR prevalences are informative of healthcare consumption rates. Analysis of co-occurrence frequencies via relative frequency analysis and observed-expected frequency ratio are informative of associations between clinical concepts, useful for biomedical research tasks such as drug repurposing and pharmacovigilance. COHD is publicly accessible through a web application-programming interface (API) and downloadable from the Figshare repository. The code is available on GitHub.

Indexed as

Databases, FactualElectronic Health RecordsData AnalysisData MiningHumansPatients

Identifiers

PMID30480666
PMCPMC6257042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.