ArticleNuclear medicine communications2019
Celiac ganglia: can they be misinterpreted on multimodal 68Ga-PSMA-11 PET/MR?
Article in Nuclear medicine communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 15 citations in OpenAlex.
- Theranostics for prostate cancer: A Canadian multidisciplinary expert report.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2026Article
- Feasibility of celiac axis delineation and treatment on combined magnetic resonance imaging and linear accelerator systems.Physics and imaging in radiation oncology · 2025Article
- PSMA-1007 Uptake in Ganglia of the Sympathetic Trunk and Its Intra-individual Reproducibility.Molecular imaging and biology · 2023Article
- Intra-Individual Comparison of Physiologic [Cancers · 2023Article
- The future of PSMA PET and WB MRI as next-generation imaging tools in prostate cancer.Nature reviews. Urology · 2022Review
- Intraindividual comparison of [EJNMMI research · 2021Article
- Intra-patient comparison of physiologicCancer imaging : the official publication of the International Cancer Imaging Society · 2021Article
- Use ofFrontiers in oncology · 2021Article
- The role of additional late PSMA-ligand PET/CT in the differentiation between lymph node metastases and ganglia.European journal of nuclear medicine and molecular imaging · 2020Article
- Dynamic patterns of [European journal of nuclear medicine and molecular imaging · 2020Article
- The "question-mark" MR anatomy of the cervico-thoracic ganglia complex: can it help to avoid mistaking it for a malignant lesion on 68Ga-PSMA-11 PET/MR?Radiology and oncology · 2019Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe objective of this study was to investigate the morphologic features and Ga-prostate-specific membrane antigen (PSMA)-11 avidity of celiac ganglia (CG) on multimodal PET/MRI. MATERIALS AND
methodsGa-PSMA-11 whole-body PET/MR examinations in 120 patients, referred for staging or follow-up of prostate cancer, were retrospectively reviewed to investigate the radiotracer uptake [maximum standardized uptake value (SUVmax)] and morphologic features (size, shape, location) of CG. Nodular, oval and longitudinal nodular, thick or with oval parts shapes of CG were regarded as mistakable with lymph nodes, whereas linear and longitudinal shapes were considered as not mistakable.
resultsOn MR scans, CG were visible in 98% (117/120) on both sides and in two patients only on the left side. Mistakable CG shape was detected in 69% (83/120) of patients on both or at least one side. The left CG were thicker (4±1.4 mm; range: 1.5-7.5 mm) than the right ones (3±1.3 mm; range: 0.5-7 mm). Mean SUVmax was 2.51±1.17 (range: 0.02-5.48) in the left CG and 2.23±1.22 (range: 0.02-5.91) in the right CG. Increased Ga-PSMA-11 uptake, SUVmax at least 2, was detected in 75% (90/120), and both - erroneous shape and elevated Ga-PSMA-ligand uptake - was observed in 55% (66/120) of all patients on both sides or at least one side.
conclusionFrequently observed, the nodular, oval and longitudinal (nodular, thick or with oval parts) shape of CG, especially of the thicker left CG, on MR scans may cause mistaking them for lymph nodes, even abnormal or metastatic. On whole-body PET/MRI, evident and sometimes high Ga-PSMA-11 uptake in CG increases the risk of a misinterpretation of them as metastases.
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