Evidence map›Paper›PMID 30480311›Full record

ArticleChemical communications (Cambridge, England)2018

Displacement chemistry-based nanopore analysis of nucleic acids in complicated matrices.

Liang Wang, Xiaohan Chen, Shuo Zhou, Golbarg M Roozbahani, Youwen Zhang, Deqiang Wang, Xiyun Guan

Open access · greenAbstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Probe-assisted detection of FeBiosensors & bioelectronics · 2024
    Article
  4. Review
  5. Nanopore Detection Assisted DNA Information Processing.Nanomaterials (Basel, Switzerland) · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Liang WangChongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing 400714, P. R. China. dqwang@cigit.ac.cn.
Xiaohan Chen
Shuo Zhou
Golbarg M Roozbahani
Youwen Zhang
Deqiang Wang
Xiyun Guan
Illinois Institute of Technology · USChongqing University · CN

Funding

Label-Free Nanopore Biosensor for Rapid, Ultrasensitive, and Multiplex Detection of Protease ActivitiesR15GM110632 · NIGMS · ILLINOIS INSTITUTE OF TECHNOLOGY · PI GUAN, XIYUN · 2014 to 2017
$746k
NIGMS NIH HHS R15 GM110632
6 · The paper itself

Abstract

To overcome the effect of other components of complicated biological samples on nanopore stochastic sensing, displacement chemical reaction was utilized to selectively extract the target nucleic acid from whole blood. Given its simplicity and high sensitivity for detecting nucleic acids, our developed displacement chemistry-based nanopore sensing strategy offers the potential for fieldable/point-of-care diagnostic applications.

Indexed as

NanoporesBiomarkersBiosensing TechniquesClinical Chemistry TestsDNA ProbesDNA, Single-StrandedHumansMicroRNAsNucleic Acid HybridizationPoint-of-Care SystemsProof of Concept StudyStochastic ProcessesBiomarkersDNA ProbesDNA, Single-StrandedMicroRNAs

Identifiers

PMID30480311
PMCPMC6800042
OpenAlexW2901761516

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.