Evidence map›Paper›PMID 30480232›Full record

ArticleJournal of Alzheimer's disease reports2017

Methylation Profiling RIN3 and MEF2C Identifies Epigenetic Marks Associated with Sporadic Early Onset Alzheimer's Disease.

Kirsty A Boden, Imelda S Barber, Naomi Clement, Tulsi Patel, Tamar Guetta-Baranes, Keeley J Brookes, Sally Chappell, Jim Craigon, Natalie H Chapman, ARUK Consortium and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of Alzheimer's disease reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Genome-wide methylomic regulation of multiscale gene networks in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Article
  6. Review
  7. Review
  8. Ras and Rab Interactor 3: From Cellular Mechanisms to Human Diseases.Frontiers in cell and developmental biology · 2022
    Review
  9. Article
  10. Article
  11. Methylation of theNeuropsychiatric disease and treatment · 2021
    Article
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Kirsty A BodenSchool of Biosciences, University of Nottingham, Nottingham, UK.
Imelda S BarberSchools of Life Sciences, University of Nottingham, Nottingham, UK.
Naomi ClementSchools of Life Sciences, University of Nottingham, Nottingham, UK.
Tulsi PatelSchools of Life Sciences, University of Nottingham, Nottingham, UK.
Tamar Guetta-BaranesSchools of Life Sciences, University of Nottingham, Nottingham, UK.
Keeley J BrookesSchools of Life Sciences, University of Nottingham, Nottingham, UK.
Sally ChappellSchools of Life Sciences, University of Nottingham, Nottingham, UK.
Jim CraigonSchool of Biosciences, University of Nottingham, Nottingham, UK.
Natalie H ChapmanSchool of Biosciences, University of Nottingham, Nottingham, UK.
ARUK Consortium
Kevin MorganSchools of Life Sciences, University of Nottingham, Nottingham, UK.
Graham B SeymourSchool of Biosciences, University of Nottingham, Nottingham, UK.
Andrew BottleySchool of Biosciences, University of Nottingham, Nottingham, UK.
University of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A number of genetic loci associate with early onset Alzheimer's disease (EOAD); however, the drivers of this disease remains enigmatic. Genome wide association and

Indexed as

Alzheimer’s diseaseepigeneticsmethylationsporadic early onset

Identifiers

PMID30480232
PMCPMC6159661
OpenAlexW2745798450

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.