Evidence map›Paper›PMID 30480050›Full record

ArticleGE Portuguese journal of gastroenterology2018

Common Variable Immunodeficiency-Associated Inflammatory Enteropathy: The New Era of Biological Therapy.

Cátia Arieira, Francisca Dias de Castro, Maria João Moreira, José Cotter

Open access · diamondAbstract read
In one paragraph

Article in GE Portuguese journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Non-celiac Enteropathies.Current gastroenterology reports · 2025
    Review
  6. Small Bowel Villous Atrophy in a Young Patient: A Challenging Diagnosis.GE Portuguese journal of gastroenterology · 2024
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Cátia ArieiraGastroenterology Department, Hospital da Senhora da Oliveira, Guimarães, Portugal.
Francisca Dias de CastroGastroenterology Department, Hospital da Senhora da Oliveira, Guimarães, Portugal.
Maria João MoreiraGastroenterology Department, Hospital da Senhora da Oliveira, Guimarães, Portugal.
José CotterGastroenterology Department, Hospital da Senhora da Oliveira, Guimarães, Portugal.
Hospital da Senhora da Oliveira Guimarães · PTCapiz State University · PH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Common variable immunodeficiency (CVID) is the most frequent form of immunodeficiency in adults. Clinical manifestations are heterogeneous with an increased susceptibility to infections and inflammatory conditions, namely autoimmune diseases, such as inflammatory bowel disease. We present the clinical case of a Caucasian female patient, 21 years old, with a past medical history of CVID, with multiple visits to the emergency department due to abdominal pain in the lower quadrants and diarrhea. Her biochemical analysis showed elevated inflammatory parameters. Stool cultures and parasitological examination of feces were negative. Ileocolonoscopy revealed lymphoid nodular hyperplasia of the terminal ileum, and the small bowel capsule endoscopy demonstrated edema and multiple pleomorphic ulcers (Lewis score = 1,104). CVID-associated inflammatory enteropathy was suspected. Budesonide 9 mg/day was started, but no positive clinical response was observed. It was decided to initiate biological therapy with infliximab. The patient's condition is currently clinically improved with no complications due to biological therapy.

Indexed as

Biological therapyCommon variable immunodeficiencyCrohn diseaseInflammatory bowel diseaseInfliximabSmall bowel capsule endoscopy

Identifiers

PMID30480050
PMCPMC6244023
OpenAlexW2790088686

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.