Evidence map›Paper›PMID 30480034›Full record

ArticleAnnals of clinical and translational neurology2018

Regulatory B cells in myasthenia gravis are differentially affected by therapies.

Vuslat Yilmaz, Solène Maillard, Frédérique Truffault, Francis Bolgert, Anthony Behin, Jean-François Regnard, Sonia Berrih-Aknin, Rozen Le Panse

Registry-linked trialAbstract read
In one paragraph

Article in Annals of clinical and translational neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07071246 (Rituximab for the Treatment of New-onset AChR-Myasthenia Gravis), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07071246 naactive not recruitingnot on this mapstarted 2022, after this paper: background citation

Rituximab for the Treatment of New-onset AChR-Myasthenia Gravis

TypeinterventionalSponsorTang-Du HospitalRan2022 to 2027Enrolled30ConditionsTreatmentArmsRituximab Injection
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Immunoregulatory Cells in Myasthenia Gravis.Frontiers in neurology · 2020
    Review
  10. Article
  11. The Role of Regulatory B Cells in Patients with Acute Myeloid Leukemia.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vuslat YilmazDepartment of Neuroscience Aziz Sancar Institute of Experimental Medical Research (DETAE) Istanbul University Istanbul Turkey.
Solène MaillardCenter of Research in Myology Sorbonne University INSERM AIM UMRS974 Paris France.
Frédérique TruffaultCenter of Research in Myology Sorbonne University INSERM AIM UMRS974 Paris France.
Francis BolgertDepartment of Neurology APHP Pitié-Salpêtrière Hospital Paris France.
Anthony BehinNeuromuscular Disease Center APHP AIM Pitié-Salpêtrière Hospital Paris France.
Jean-François RegnardDepartment of Thoracic Surgery Cochin Hospital of Paris APHP René Descartes University Paris France.
Sonia Berrih-AkninCenter of Research in Myology Sorbonne University INSERM AIM UMRS974 Paris France.
Rozen Le PanseCenter of Research in Myology Sorbonne University INSERM AIM UMRS974 Paris France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We analyzed the number and functionality of regulatory B (Breg) cells in well-defined myasthenia gravis patients. We first showed a decreased number of circulating CD19

Identifiers

PMID30480034
PMCPMC6243377

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.