Evidence map›Paper›PMID 30479999›Full record

ArticleERJ open research2018

Randomised controlled trial of cognitive behavioural therapy in COPD.

Karen Heslop-Marshall, Christine Baker, Debbie Carrick-Sen, Julia Newton, Carlos Echevarria, Chris Stenton, Michelle Jambon, Joanne Gray, Kim Pearce, Graham Burns and 1 more

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 5 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 5 syntheses or guidelines pooled it, 97 citations in OpenAlex.

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  3. What conservative interventions can improve the long-term quality of life, depression, and anxiety of individuals with stable COPD? A systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Karen Heslop-MarshallChest Clinic, Newcastle upon Tyne Hospitals NHS Foundation Trust, RVI Hospital, Newcastle upon Tyne, UK.
Christine BakerDept of Clinical Health Psychology, Newcastle upon Tyne Hospitals NHS Foundation Trust, RVI Hospital, Newcastle upon Tyne, UK.
Debbie Carrick-SenNursing Dept, School of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Julia NewtonInstitute of Cellular Medicine, Medical School, Newcastle University, Newcastle upon Tyne, UK.
Carlos EchevarriaChest Clinic, Newcastle upon Tyne Hospitals NHS Foundation Trust, RVI Hospital, Newcastle upon Tyne, UK.
Chris StentonChest Clinic, Newcastle upon Tyne Hospitals NHS Foundation Trust, RVI Hospital, Newcastle upon Tyne, UK.
Michelle JambonCommunity Chest Team, Newcastle Upon Tyne Hospitals NHS Foundation Trust, RVI Hospital, Newcastle upon Tyne, UK.
Joanne GrayFaculty of Health and Life Science, Northumbria University, Newcastle upon Tyne, UK.
Kim PearceInstitute of Cellular Medicine, Medical School, Newcastle University, Newcastle upon Tyne, UK.
Graham BurnsChest Clinic, Newcastle upon Tyne Hospitals NHS Foundation Trust, RVI Hospital, Newcastle upon Tyne, UK.
Anthony De SoyzaInstitute of Cellular Medicine, Medical School, Newcastle University, Newcastle upon Tyne, UK.ORCID https://orcid.org/0000-0002-8566-0344
Newcastle upon Tyne Hospitals NHS Foundation Trust · GBNewcastle University · GBHeart of England NHS Foundation Trust · GBNorthumbria University · GB

Funding

Department of Health CAT CDRF 10-023
6 · The paper itself

Abstract

Anxiety is an important comorbidity in chronic obstructive pulmonary disease (COPD). We investigated if cognitive behavioural therapy (CBT), delivered by respiratory nurses, reduced symptoms of anxiety and was cost-effective. Patients with COPD and anxiety were randomised to CBT or self-help leaflets. Anxiety, depression and quality of life were measured at baseline, 3, 6 and 12 months. A cost-effectiveness analysis was conducted from a National Health Service hospital perspective and quality-adjusted life-years estimated using the EuroQol-5D questionnaire. In total, 279 patients were recruited. Group mean change from baseline to 3 months in the Hospital Anxiety and Depression Anxiety Subscale was 3.4 (95% CI 2.62-4.17, p<0.001) for the CBT group and 1.88 (95% CI 1.19-2.55, p<0.001) in the leaflet group. The CBT group was superior to leaflets at 3 months (mean difference in the Hospital Anxiety and Depression Anxiety Subscale was 1.52, 95% CI 0.49-2.54, p=0.003). Importantly, the CBT intervention was more cost-effective than leaflets at 12 months, significantly lowering hospital admissions and attendance at emergency departments. CBT delivered by respiratory nurses is a clinically and cost-effective treatment for anxiety in patients with COPD relative to self-help leaflets.

Identifiers

PMID30479999
PMCPMC6250562
OpenAlexW2901128859

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.