Evidence map›Paper›PMID 30479938›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2018

Biodegradable 2D Fe-Al Hydroxide for Nanocatalytic Tumor-Dynamic Therapy with Tumor Specificity.

Zhenbang Cao, Liang Zhang, Kang Liang, Soshan Cheong, Cyrille Boyer, J Justin Gooding, Yu Chen, Zi Gu

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Review
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  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Layered Double Hydroxides: A Novel Promising 2D Nanomaterial for Bone Diseases Treatment.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhenbang CaoSchool of Chemical Engineering and Australian Centre for NanoMedicine (ACN) University of New South Wales Sydney NSW 2052 Australia.
Liang ZhangDepartment of Ultrasound the First Affiliated Hospital of Chongqing Medical University Chongqing 400010 China.
Kang LiangSchool of Chemical Engineering and Australian Centre for NanoMedicine (ACN) University of New South Wales Sydney NSW 2052 Australia.
Soshan CheongElectron Microscope Unit University of New South Wales Sydney NSW 2052 Australia.
Cyrille BoyerSchool of Chemical Engineering and Australian Centre for NanoMedicine (ACN) University of New South Wales Sydney NSW 2052 Australia.
J Justin GoodingSchool of Chemistry ARC Centre of Excellence in Convergent Bio-Nano Science and Technology and Australian Centre for NanoMedicine (ACN) University of New South Wales Sydney NSW 2052 Australia.
Yu ChenState Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of Ceramics Chinese Academy of Sciences Shanghai 200050 China.ORCID 0000-0002-8206-3325
Zi GuSchool of Chemical Engineering and Australian Centre for NanoMedicine (ACN) University of New South Wales Sydney NSW 2052 Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Therapeutic nanocatalysis has emerged as an intriguing strategy for efficient cancer-specific therapy, but the traditional inorganic nanocatalysts suffer from low catalytic efficiency and difficulty in biodegradation, hindering their further clinical translation. Herein, a tumor microenvironment-triggered, biodegradable and biocompatible nanocatalyst employing 2D hydroxide nanosheet is presented, and is shown to have high catalytic capacity to efficiently produce abundant hydroxyl radicals under the tumor microenvironment and consequently kill tumor cells selectively. A polyethylene glycol (PEG)-conjugated Fe

Indexed as

2D nanosheetslayered double hydroxidenanomedicinetherapeutic catalysistumor microenvironment responsiveness

Identifiers

PMID30479938
PMCPMC6247031

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.