ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2018
Antifouling Super Water Absorbent Supramolecular Polymer Hydrogel as an Artificial Vitreous Body.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 92 citations in OpenAlex.
- Novel Vitreous Substitutes in Animal and Human Models: A Systematic Review.BioMed research international · 2026Pooled it
- Chain entanglement-stabilized injectable zwitterionic hydrogel for vitreous replacement and retinal tamponade.National science review · 2026Article
- Anion-π Interaction-Triggered Self-Healing Zwitterionic Hydrogel as an Immunocompatible Platform for Injectable Therapies.Advanced healthcare materials · 2026Article
- Unveiling the rheological secrets of hydrogels: from lab to clinical translation.RSC advances · 2026Review
- Replacing the vitreous body with hydrogels: Rationale and strategies.Progress in retinal and eye research · 2025Review
- Dual-Crosslinked Betaine-Based Amphiphilic Hydrogel as a Promising Vitreous Substitute: Anti-Adhesion, Anti-Fouling, and Anti-Cell Proliferation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Hydrogel-Based Vitreous Substitutes.International journal of molecular sciences · 2025Review
- Research progress of photo-crosslink hydrogels in ophthalmology: A comprehensive review focus on the applications.Materials today. Bio · 2024Review
- Smart molecules in ophthalmology: Hydrogels as responsive systems for ophthalmic applications.Smart molecules : open access · 2024Review
- Construction of multifunctional hydrogel with metal-polyphenol capsules for infected full-thickness skin wound healing.Bioactive materials · 2023Article
- Advances in Polysaccharide- and Synthetic Polymer-Based Vitreous Substitutes.Pharmaceutics · 2023Review
- Vitreous Substitutes from Bench to the Operating Room in a Translational Approach: Review and Future Endeavors in Vitreoretinal Surgery.International journal of molecular sciences · 2023Review
- 3D printed biomimetic epithelium/stroma bilayer hydrogel implant for corneal regeneration.Bioactive materials · 2022Article
- Microgel reinforced zwitterionic hydrogel coating for blood-contacting biomedical devices.Nature communications · 2022Article
- Article
- An in situ-forming polyzwitterion hydrogel: Towards vitreous substitute application.Bioactive materials · 2021Article
- Bio-inspired poly-DL-serine materials resist the foreign-body response.Nature communications · 2021Article
- A Long-Acting Curcumin Nanoparticle/In Situ Hydrogel Composite for the Treatment of Uveal Melanoma.Pharmaceutics · 2021Article
- Rational Design of Thermosensitive Hydrogel to Deliver Nanocrystals with Intranasal Administration for Brain Targeting in Parkinson's Disease.Research (Washington, D.C.) · 2021Article
- Anti-Biofouling Polymers with Special Surface Wettability for Biomedical Applications.Frontiers in bioengineering and biotechnology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, there has been a high expectation that high water absorbent hydrogels can be developed as an artificial vitreous body. However, the drawbacks associated with in vivo instability, biofouling, uncontrollable in situ reaction time, and injection-induced precrosslinked fragmentation preclude their genuine use as vitreous substitutes. Here, a supramolecular binary copolymer hydrogel termed as PNAGA-PCBAA by copolymerization of
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.