Evidence map›Paper›PMID 30479782›Full record

ArticleJMM case reports2018

Case report: A fatal case of cryptococcosis in an immunocompetent patient due to

M Bauer, C Wickenhauser, A Haak, N Pazaitis, U Siebolts, C Mawrin, C Strauss, V Rickerts, D Stoevesandt, O A Cornely and 2 more

Open access · hybridAbstract readCase Reports
In one paragraph

Article in JMM case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Ophthalmic manifestations ofInternational journal of ophthalmology · 2022
    Article
  2. Article
  3. Article
  4. Cryptococcal meningitis in non-HIV patients in the State of Amazonas, Northern Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Article
  5. mBio · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

M BauerInstitute of Pathology, Martin-Luther-University Halle-Wittenberg, Halle/Saale, Germany.
C WickenhauserInstitute of Pathology, Martin-Luther-University Halle-Wittenberg, Halle/Saale, Germany.
A HaakInstitute of Pathology, Martin-Luther-University Halle-Wittenberg, Halle/Saale, Germany.
N PazaitisInstitute of Pathology, Martin-Luther-University Halle-Wittenberg, Halle/Saale, Germany.
U SieboltsInstitute of Pathology, Martin-Luther-University Halle-Wittenberg, Halle/Saale, Germany.
C MawrinInstitute of Neuropathology, Otto-von-Guericke-University, Magdeburg, Germany.
C StraussDepartment of Neurosurgery, Martin-Luther-University Halle-Wittenberg, Halle/Saale, Germany.
V RickertsFG 16, Consultant Laboratory for Cryptococcosis, Scedosporiosis and Imported Systemic Mycoses, Robert-Koch-Institute, Berlin, Germany.
D StoevesandtInstitute of Radiology, Martin-Luther-University Halle-Wittenberg, Halle/Saale, Germany.
O A CornelyCologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Department I of Internal Medicine, Clinical Trials Centre Cologne (ZKS Köln), University of Cologne, Cologne, Germany.
J F MeisDepartment Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.
F HagenDepartment Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.
Martin Luther University Halle-Wittenberg · DECanisius-Wilhelmina Ziekenhuis · NLCologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases · DEOtto-von-Guericke University Magdeburg · DERadboud University Nijmegen · NLRobert Koch Institute · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCryptococcosis in immunocompetent adults is a rare disease in Europe, mostly induced by members of the CASE PRESENTATION: A 49-year-old woman with a three weeks history of headache was admitted to the hospital due to discrete ataxia and impaired vision. Cranial magnetic resonance imaging (MRI) showed a contrast-enhancing mass in the cerebellum. Further investigations detected a slight leukocytosis and a single subpleural nodule in the right inferior lung lobe. The cerebral lesion was surgically removed, and a direct frozen section only showed an unspecific inflammation. In the course of her admission she developed non-treatable cerebral edema and died ten days after surgical intervention. Histopathological examination of the surgical specimen and postmortem evaluation of the lung and the cerebrum demonstrated fungal elements. Molecular identification of the fungal elements in formalin-fixed paraffin-embedded tissue lead to the diagnosis of cryptococcosis induced by

conclusionCryptococcosis due to

Indexed as

cerebral disseminationCryptococcus deuterogattiiCryptococcus gattiiendemic areasimmunocompetent hostpulmonary cryptococcosis

Identifiers

PMID30479782
PMCPMC6249430
OpenAlexW2897416556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.