Evidence map›Paper›PMID 30479672›Full record

ArticleTherapeutic advances in medical oncology2018

Assessing response to neo-adjuvant therapy in locally advanced rectal cancer using Intra-voxel Incoherent Motion modelling by DWI data and Standardized Index of Shape from DCE-MRI.

Antonella Petrillo, Roberta Fusco, Vincenza Granata, Salvatore Filice, Mario Sansone, Daniela Rega, Paolo Delrio, Francesco Bianco, Giovanni Maria Romano, Fabiana Tatangelo and 2 more

Open access · goldAbstract read
In one paragraph

Article in Therapeutic advances in medical oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

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  6. Immunotherapy Assessment: A New Paradigm for Radiologists.Diagnostics (Basel, Switzerland) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Antonella PetrilloRadiology Unit, 'Istituto Nazionale Tumori, IRCCS, Fondazione G Pascale', Naples, Italy.
Roberta FuscoRadiology Unit, 'Istituto Nazionale Tumori, IRCCS, Fondazione G Pascale', Via Mariano Semmola, Naples 80131, Italy.
Vincenza GranataRadiology Unit, 'Istituto Nazionale Tumori, IRCCS, Fondazione G Pascale', Naples, Italy.
Salvatore FiliceRadiology Unit, 'Istituto Nazionale Tumori, IRCCS, Fondazione G Pascale', Naples, Italy.
Mario SansoneDepartment of Electrical Engineering and Information Technologies, University 'Federico II' of Naples, Naples, Italy.
Daniela RegaGastrointestinal Surgical Oncology Unit, 'Istituto Nazionale Tumori, IRCCS, Fondazione G Pascale', Naples, Italy.
Paolo DelrioGastrointestinal Surgical Oncology Unit, 'Istituto Nazionale Tumori, IRCCS, Fondazione G Pascale', Naples, Italy.
Francesco BiancoGastrointestinal Surgical Oncology Unit, 'Istituto Nazionale Tumori, IRCCS, Fondazione G Pascale', Naples, Italy.
Giovanni Maria RomanoGastrointestinal Surgical Oncology Unit, 'Istituto Nazionale Tumori, IRCCS, Fondazione G Pascale', Naples, Italy.
Fabiana TatangeloDiagnostic Pathology Unit, 'Istituto Nazionale Tumori, IRCCS, Fondazione G Pascale', Naples, Italy.
Antonio AvalloneGastrointestinal Medical Oncology Unit, 'Istituto Nazionale Tumori, IRCCS, Fondazione G Pascale', Naples, Italy.
Biagio PecoriRadiotherapy Unit, 'Istituto Nazionale Tumori, IRCCS, Fondazione G Pascale', Naples, Italy.
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur aim was to investigate preoperative chemoradiation therapy (pCRT) response in locally advanced rectal cancer (LARC) comparing standardized index of shape (SIS) obtained from dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) with intravoxel-incoherent-motion-modelling-derived parameters by diffusion-weighted imaging (DWI). MATERIALS AND

methodsEighty-eight patients with LARC were subjected to MRI before and after pCRT. Apparent diffusion coefficient (ADC), tissue diffusion (D

resultsA total of 52 patients were classified as responders (tumour regression grade; TRG ⩽ 2) and 36 as not-responders (TRG > 3). Mann-Whitney

conclusionSIS allows assessment of preoperative treatment response with high accuracy guiding the surgeon

Indexed as

assessment responsediffusion parameters changeLARCneoadjuvant therapySIS change

Identifiers

PMID30479672
PMCPMC6243411
OpenAlexW2900828349

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.