Evidence map›Paper›PMID 30479668›Full record

ArticleDiabetology & metabolic syndrome2018

Neck circumference is associated with non-traditional cardiovascular risk factors in individuals at low-to-moderate cardiovascular risk: cross-sectional analysis of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).

B Almeida-Pititto, I T Silva, A C Goulart, M I H Fonseca, M S Bittencourt, R D Santos, M Blaha, S Jones, P P Toth, K Kulakarni and 4 more

Open access · goldAbstract read
In one paragraph

Article in Diabetology & metabolic syndrome, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

B Almeida-Pititto1Department of Preventive Medicine, Federal University of Sao Paulo, Rua Botucatu 740, São Paulo, SP 04023900 Brazil.
I T Silva2School of Public Health, University of São Paulo, Av. Dr. Arnaldo, 715, São Paulo, SP 01246-904 Brazil.
A C Goulart3Department of Internal Medicine, University of São Paulo, Av. Lineu Prestes 2565, 4th Floor, São Paulo, SP 05508-000 Brazil.
M I H Fonseca2School of Public Health, University of São Paulo, Av. Dr. Arnaldo, 715, São Paulo, SP 01246-904 Brazil.
M S Bittencourt3Department of Internal Medicine, University of São Paulo, Av. Lineu Prestes 2565, 4th Floor, São Paulo, SP 05508-000 Brazil.
R D Santos5Lipid Clinic Heart Institute (InCor), University of Sao Paulo, Medical School Hospital, Av. Dr. Enéas de Carvalho Aguiar 44, São Paulo, 01246-000 Brazil.
M Blaha6Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Blalock 524 D1, 600 N. Wolfe St, Baltimore, MD USA.
S Jones6Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Blalock 524 D1, 600 N. Wolfe St, Baltimore, MD USA.
P P Toth6Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Blalock 524 D1, 600 N. Wolfe St, Baltimore, MD USA.
K KulakarniVAP Diagnostics Laboratory, 201 London Pkwy, Birmingham, AL 35211 USA.
P A Lotufo4Center for Clinical and Epidemiological Research, Hospital Universitário, University of São Paulo, Av. Lineu Prestes 2565, 3rd Floor, São Paulo, 05508-000 Brazil.
I M Bensenor4Center for Clinical and Epidemiological Research, Hospital Universitário, University of São Paulo, Av. Lineu Prestes 2565, 3rd Floor, São Paulo, 05508-000 Brazil.
S R G Ferreira2School of Public Health, University of São Paulo, Av. Dr. Arnaldo, 715, São Paulo, SP 01246-904 Brazil.
ELSA Research Group
Universidade de São Paulo · BRJohns Hopkins University · USHospital Universitário da Universidade de São Paulo · BRUniversidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeck circumference (NC) is associated with traditional cardiovascular risk factors (CVRF), but its usefulness to identify earlier atherogenic risk has been scarcely examined. Associations of NC with non-traditional CVRF were investigated in participants at low-to-moderate risk from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).

methods807 individuals (35-54 years) without obesity, diabetes or cardiovascular disease was stratified into quartiles of NC (cut-off for men: 36.5; 37.9 and 39.5 cm; women: 31.4; 32.5 and 34 cm) and traditional and non-traditional risk factors (lipoprotein subfractions by Vertical Auto Profile, adiponectin, leptin, E-selectin) were compared across groups. In linear regression models, associations of NC with non-traditional risk factors were tested for the entire sample and for low-risk group (≤ 2 CVRF).

resultsIn both sexes, BMI, waist circumference, systolic and diastolic blood pressure, fasting and 2-h plasma glucose, HOMA-IR, triglycerides, leptin, E-selectin, small dense LDL-cholesterol, IDL-cholesterol, VLDL

conclusionOur findings indicate that measurement of NC may be useful for an earlier identification of unfavorable atherogenic metabolic profile in middle-aged individuals at lower cardiovascular risk level.

Indexed as

AdipocytokinesCardiovascular risk factorsE-SelectinLipoprotein subfractionsNeck circumferenceNon-traditional risk factors

Identifiers

PMID30479668
PMCPMC6247673
OpenAlexW2901634474

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.