SynthesisJournal of foot and ankle research2018
Antibiotic prophylaxis in foot and ankle surgery: a systematic review of the literature.
Synthesis in Journal of foot and ankle research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Plasma and tissue concentrations of 2 g prophylactic cefazolin prior to lower extremity surgery.Antimicrobial agents and chemotherapy · 2024Trial
- Assessment of Risk Factors for Surgical Site Infection in Diabetic Patients Undergoing Elective Surgery.Cureus · 2026Article
- Article
- Complications in nail surgery and prevention strategies: a comprehensive review.Dermatology reports · 2025Article
- Infections in foot and ankle bone surgery: Comparison between single- and multiday use of postoperative oral antibiotics.Medicine · 2025Article
- No Routine Control Measurements of C-Reactive Protein in Uneventful Postoperative Evolution After Debridement for Infected (Diabetic) Foot Surgery.Journal of clinical medicine · 2025Article
- Comparison of Partial Nail Avulsion With or Without Phenolization in the Management of Ingrown Toenails.Cureus · 2025Article
- Predicting surgical site infections after open reduction and internal fixation for ankle fractures.Archives of orthopaedic and trauma surgery · 2025Article
- What Is the Risk of Irrigation and Debridement Following Foot and Ankle Surgery? Development of a Risk Severity Scoring System.Clinical orthopaedics and related research · 2024Article
- Therapy for Non-Diabetic Foot Infections After Orthopedic Foot and Ankle Surgery: The Duration of Post-Debridement Antibiotic Treatment Does Not Alter Failure Risk.Life (Basel, Switzerland) · 2024Article
- Perioperative Antibiotic Choice Does Not Affect Wound Complications in the Operative Treatment of Ankle Fractures.Cureus · 2024Article
- A Prospective Evaluation for a Possible Safe Skin Bridge in Elective Foot Surgery.Foot & ankle orthopaedics · 2024Article
- Risk Factors for Surgical Site Infections in Elective Orthopedic Foot and Ankle Surgery: The Role of Diabetes Mellitus.Journal of clinical medicine · 2023Article
- Minimally invasive treatment and internal fixation vs. extended lateral approach in calcaneus fractures of thalamic interest.Experimental and therapeutic medicine · 2022Article
- Seasonal effect on the incidence of post-operative wound complications after trauma-related surgery of the foot, ankle and lower leg.Archives of orthopaedic and trauma surgery · 2020Article
- Risk factors for infection following ingrowing toenail surgery: a retrospective cohort study.Journal of foot and ankle research · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWith the advent of bacterial resistance, it is important now more than ever to evaluate use of antibiotic chemoprophylaxis in foot and ankle surgery. Within this area of the body there may be less dissection, surgery time with smaller incisions and importantly smaller sizes of implanted fixation as compared to other bone and joint procedures. Our objective was to systematically evaluate the quality of evidence behind existing guidelines. METHODOLOGY: A systematic literature search was performed: MEDLINE, CINHAL, EMBASE and the Cochrane library from 1990 up to March 2018. To avoid omitting any studies on the subject, Google Scholar was also used. The inclusion criterion were studies exploring perioperative antibiotic use, postoperative infection rates in elective foot and ankle surgery and studies associated with this subject evaluating antibiotic use in clean elective foot and ankle surgery. The exclusion criterion being studies upon contaminated or dirty surgery or those which were inclusive of procedures proximal to the foot and ankle.
resultsOverall 11 studies met the inclusion criteria. From the grading of evidence, 2 level one and 4 level two studies were recognised. These studies ranked relatively highly in comparison to 5 studies that were graded as level three and level four tiers of evidence. Results of SSI rates found within this systematic review ranged from 0% to 9.4% of overall postoperative infections encountered after foot and ankle surgery in the studies analysed.
conclusionWhilst fragmented, aspects of antibiotic chemoprophylaxis are established fields in elective surgery with a growing body of evidence. Evidence for antibiotic use however, specifically within elective foot and ankle surgery, is lacking. This systematic review is a seminal paper which delivers an impression of the most influential literature within the field of foot and ankle surgery, with the aim being to entice conclusions and guide future research.
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Registered trials
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