ArticleJournal of contemporary brachytherapy2018
High-dose-rate interstitial brachytherapy in recurrent head and neck cancer: an effective salvage option.
Article in Journal of contemporary brachytherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 21 citations in OpenAlex.
- The Role of Brachytherapy in the Management of Oral Squamous Cell Carcinoma: A Systematic Review.Journal of clinical medicine · 2025Review
- Positron emission tomography directed re-irradiation using volumetric modulated arc technique in recurrent head and neck squamous cell carcinoma.Scientific reports · 2025Article
- Review
- Is There Still a Place for Brachytherapy in the Modern Treatment of Early-Stage Oral Cancer?Cancers · 2022Review
- Brachytherapy Approach UsingPharmaceutics · 2021Article
- Salvage brachytherapy with or without external beam radiotherapy for oral or oropharyngeal squamous cell carcinomas in previously irradiated areas: carcinologic and toxicity outcomes of 25 patients.Journal of contemporary brachytherapy · 2021Article
- Brachytherapy in head and neck malignancies: Indian Brachytherapy Society (IBS) recommendations and guidelines.Journal of contemporary brachytherapy · 2020Article
- Per-oral interstitial brachytherapy catheter insertion for boost in case of recurrent tonsillar carcinoma: dosimetry and clinical outcome.BJR case reports · 2020Article
- Carotid dosimetry after re-irradiation withJournal of contemporary brachytherapy · 2019Article
- Article
Corrections and comments
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Authors and funding
14 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeHigh-dose-rate (HDR) interstitial brachytherapy has an established role in head and neck malignancies and offers good survival rates; however, there is scant data on improved local control (LC) and treatment-related complications in recurrent cases. We present our results in patients with recurrent head and neck cancers treated with HDR interstitial brachytherapy. MATERIAL AND
methodsTwenty-five patients with recurrent head and neck cancers were treated with HDR interstitial brachytherapy using Iridium 192 between 2009 and 2016. Of these, 75% received radical brachytherapy, and 25% received external beam radiation therapy (EBRT) followed by brachytherapy boost. Treatment sites included oral cavity (15/25) and oropharynx (10/25). Median dose of 4.5 Gy was administered twice per day, with median total brachytherapy dose of 40.5 Gy in radical and 27 Gy for EBRT cases.
resultsWith median follow-up of 25 months, 4 local recurrences were observed within first year of follow-up. Two-year local control and overall survival outcomes for the entire group were 75% and 68%, respectively. Local control rate with radical BRT vs. BRT as a boost following EBRT was found to be significant (2-year LCR 62% vs. 85%;
conclusionsResults of HDR interstitial brachytherapy have shown acceptable local control and overall survival rates along with tolerable toxicities and morbidity in recurrent head and neck cancers.
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