Evidence map›Paper›PMID 30479587›Full record

ArticleDose-response : a publication of International Hormesis Society

Sodium Dichloroacetate Pharmacological Effect as Related to Na-K-2Cl Cotransporter Inhibition in Rats.

Jūratė Stanevičiūtė, Milda Juknevičienė, Jolita Palubinskienė, Ingrida Balnytė, Angelija Valančiūtė, Rūta Vosyliūtė, Kęstutis Sužiedėlis, Vaiva Lesauskaitė, Donatas Stakišaitis

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Dose-response : a publication of International Hormesis Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jūratė StanevičiūtėDepartment of Histology and Embryology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Milda JuknevičienėDepartment of Histology and Embryology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Jolita PalubinskienėDepartment of Histology and Embryology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Ingrida BalnytėDepartment of Histology and Embryology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Angelija ValančiūtėDepartment of Histology and Embryology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Rūta VosyliūtėDepartment of Histology and Embryology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Kęstutis SužiedėlisLaboratory of Molecular Oncology, National Cancer Institute, Vilnius, Lithuania.
Vaiva LesauskaitėInstitute of Cardiology of Lithuanian University of Health Sciences, Kaunas, Lithuania.
Donatas StakišaitisDepartment of Histology and Embryology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Lithuanian University of Health Sciences · LTNational Cancer Institute · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study objective was to investigate a possible sodium dichloroacetate (DCA) pharmacological mechanism causing an increase in diuresis in rats. The aim was to define characteristics of 24-hour urinary Na

Indexed as

dichloroacetateionskidneyNKCC1NKCC2thymus

Identifiers

PMID30479587
PMCPMC6247491
OpenAlexW2900651936

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.