Evidence map›Paper›PMID 30479465›Full record

ArticleWorld journal of gastroenterology2018

Mode of delivery by an ulcerative colitis mother in a case of twins: Immunological differences in cord blood and placenta.

Garett Dunsmore, Petya Koleva, Reed Taylor Sutton, Lindsy Ambrosio, Vivian Huang, Shokrollah Elahi

Open access · hybridAbstract readCase Reports
In one paragraph

Article in World journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. CD71Journal for immunotherapy of cancer · 2023
    Article
  5. Hematopoietic responses to SARS-CoV-2 infection.Cellular and molecular life sciences : CMLS · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. CD71Frontiers in immunology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Garett DunsmoreDepartment of Dentistry and Department of Medical Microbiology and Immunology, University of Alberta, Edmonton T6G2E1, Alberta, Canada.
Petya KolevaDepartment of Dentistry, University of Alberta, Edmonton T6G2E1 Alberta, Canada.
Reed Taylor SuttonDivision of Gastroenterology, University of Alberta, Edmonton T6G2E1, Alberta, Canada.
Lindsy AmbrosioDivision of Gastroenterology, University of Alberta, Edmonton T6G2E1, Alberta, Canada.
Vivian HuangDivision of Gastroenterology, University of Alberta, Edmonton, T6G 2E1, Alberta, Canada and Division of Gastroenterology, University of Toronto, Mount Sinai Hospital, Sinai Health System, Toronto, M5G 1X5, Ontario, Canada.
Shokrollah ElahiDepartment of Dentistry and Department of Medical Microbiology and Immunology, University of Alberta, Edmonton T6G2E1, Alberta, Canada. elahi@ualberta.ca.
Mount Sinai Hospital · CASinai Health System · CAUniversity of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo understand the effects of delivery mode on the immune cells frequency and function in cord blood and placenta.

methodsWe evaluated immunological differences in cord blood and placental tissues for a case of twins one of which delivered vaginally while the other delivered by caesarian section (C-section). Cord blood mononuclear cells were isolated and placenta tissues were processed for cell isolation. Immune phenotyping was performed by flow cytometry methods following staining for T cells, natural killer (NK) cells, monocytes, neutrophils and CD71

resultsWe found lower percentages of immune cells (

conclusionMode of delivery impacted immune cells profile in cord blood/placenta. In particular frequency of immunosuppressive CD71

Indexed as

TwinsAntigens, CDBiomarkersColitis, UlcerativeDelivery, ObstetricErythroid CellsFemaleFetal BloodFlow CytometryHumansInfant, NewbornLeukocytesPlacentaPregnancyReceptors, TransferrinAntigens, CDBiomarkersCD71 antigenReceptors, TransferrinCaesarian sectionCD71+ erythroid cellsCord bloodImmunophenotypingPlacental tissuesTwinsVaginal delivery

Identifiers

PMID30479465
PMCPMC6235805
OpenAlexW2900834229

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.