Evidence map›Paper›PMID 30479248›Full record

Observational studyThe American journal of tropical medicine and hygiene2019

A Prospective Comparison of Quick Sequential Organ Failure Assessment, Systemic Inflammatory Response Syndrome Criteria, Universal Vital Assessment, and Modified Early Warning Score to Predict Mortality in Patients with Suspected Infection in Gabon.

Manus Schmedding, Bayode R Adegbite, Susan Gould, Justin O Beyeme, Akim A Adegnika, Martin P Grobusch, Michaëla A M Huson

Abstract readComparative StudyObservational Study
In one paragraph

Observational study in The American journal of tropical medicine and hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Manus SchmeddingCentre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
Bayode R AdegbiteCentre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
Susan GouldCentre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
Justin O BeyemeAlbert Schweitzer Hospital, Lambaréné, Gabon.
Akim A AdegnikaGerman Center for Infection Research, Institute of Tropical Medicine, University of Tübingen and Partner site Tübingen, Tübingen, Germany.
Martin P GrobuschGerman Center for Infection Research, Institute of Tropical Medicine, University of Tübingen and Partner site Tübingen, Tübingen, Germany.
Michaëla A M HusonDivision of Infectious Diseases, Center of Tropical Medicine and Travel Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Centre de Recherche Médicales de Lambaréné · GAUniversity of Amsterdam · NLAlbert Schweitzer Hospital · GAAmsterdam UMC Location University of Amsterdam · NLGerman Center for Infection Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The quick sequential organ failure assessment (qSOFA) score has been proposed for risk stratification of emergency room patients with suspected infection. Its use of simple bedside observations makes qSOFA an attractive option for resource-limited regions. We prospectively assessed the predictive ability of qSOFA compared with systemic inflammatory response syndrome (SIRS), universal vital assessment (UVA), and modified early warning score (MEWS) in a resource-limited setting in Lambaréné, Gabon. In addition, we evaluated different adaptations of qSOFA and UVA in this cohort and an external validation cohort from Malawi. We included 279 cases, including 183 with an ad hoc (suspected) infectious disease diagnosis. Overall mortality was 5%. In patients with an infection, oxygen saturation, mental status, human immunodeficiency virus (HIV) status, and all four risk stratification score results differed significantly between survivors and non-survivors. The UVA score performed best in predicting mortality in patients with suspected infection, with an area under the receiving operator curve (AUROC) of 0.90 (95% confidence interval [CI]: 0.78-1.0,

Indexed as

Organ Dysfunction ScoresAdultArea Under CurveCommunicable DiseasesFemaleGastrointestinal DiseasesHealth ResourcesHIV InfectionsHumansIntensive Care UnitsMalariaMaleMiddle AgedPredictive Value of TestsProspective StudiesROC Curve

Identifiers

PMID30479248
PMCPMC6335900
OpenAlexW2902849723

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.