SynthesisInternational psychogeriatrics2019
Non-pharmacological interventions for depression/anxiety in older adults with physical comorbidities affecting functioning: systematic review and meta-analysis.
Synthesis in International psychogeriatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Non-pharmacological mental health interventions for older adults in Mexico: a systematic review.Frontiers in aging · 2026Pooled it
- Effectiveness of late-life depression interventions on functional limitations: A systematic review.International journal of mental health nursing · 2022Pooled it
- Epidemiology of depressive disorders in people living with hypertension in Africa: a systematic review and meta-analysis.BMJ open · 2020Pooled it
- A Scoping Review of Integrated Care Models for Managing Depression in Older Adults.Geriatrics (Basel, Switzerland) · 2026Review
- Movement as therapy an analytical study of the role of physical activity in building strong mental health for older adults.Frontiers in public health · 2026Article
- Pilot trial protocol: community intervention to improve depressive symptoms among Peruvian older adults.Pilot and feasibility studies · 2024Article
- Effectiveness of Problem-Solving Therapy in Improving Patient Mental Health, Function, Quality of Life, and Mortality Post-Stroke: A Systematic Review.Behavioral sciences (Basel, Switzerland) · 2024Review
- Article
- PROTOCOL: Non-pharmacological interventions for older people with a diagnosis of depression: An evidence and gap map.Campbell systematic reviews · 2023Article
- Comorbidity between major depressive disorder and physical diseases: a comprehensive review of epidemiology, mechanisms and management.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2023Article
- Internet-based and mobile-based cognitive behavioral therapy for chronic diseases: a systematic review and meta-analysis.NPJ digital medicine · 2023Review
- The Buffering Role of Self-compassion in the Association Between Loneliness with Depressive Symptoms: A Cross-Sectional Survey Study Among Older Adults Living in Residential Care Homes During COVID-19.International journal of mental health and addiction · 2023Article
- Self-management of depression and anxiety amongst frail older adults in the United Kingdom: A qualitative study.PloS one · 2022Article
- Supporting frail older people with depression and anxiety: a qualitative study.Aging & mental health · 2020Article
- High intensity endurance training is associated with better quality of life, but not with improved cognitive functions in elderly marathon runners.Scientific reports · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo review the effectiveness of non-pharmacological interventions in older adults with depression or anxiety and comorbidities affecting functioning.
designSystematic review and meta-analysis of randomized controlled trials, including searches of 10 databases (inception-Jul 2017).
settingHome/community.
participantsPeople aged 60 and over experiencing functional difficulties from physical or cognitive comorbidities and have symptoms or a diagnosis of depression and/or anxiety.
interventionsNon-pharmacological interventions targeted at depression/anxiety. MEASUREMENTS: We extracted outcome data on depressive symptoms, quality of life, functioning, and service use. We used random effects meta-analysis to pool study data where possible. Two authors assessed the risk of bias using the Cochrane Risk of Bias tool.
resultsWe identified 14 eligible trials including 2099 randomized participants and two subgroup analyses. Problem-solving therapy (PST) reduced short-term clinician-rated depressive symptoms (n = 5 trials, mean difference in Hamilton Depression Rating Scale score -4.94 [95% CI -7.90 to -1.98]) but not remission, with limited evidence for effects on functioning and quality of life. There was limited high-quality evidence for other intervention types. Collaborative care did not appear to affect depressive symptoms, functioning, or quality of life; and had mixed evidence for effects upon remission. No intervention consistently affected service use, but trials were limited by small sample sizes and short follow-up periods. No anxiety interventions were identified.
conclusionPST may reduce depressive symptoms post-intervention in older people with depression and functional impairments. Collaborative care appears to have few effects in this population. Future research needs to assess cost-effectiveness, long-term outcomes, and anxiety interventions for this population.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.