Evidence map›Paper›PMID 30479136›Full record

ArticleActa radiologica (Stockholm, Sweden : 1987)2019

Validation and reproducibility of cardiovascular 4D-flow MRI from two vendors using 2 × 2 parallel imaging acceleration in pulsatile flow phantom and in vivo with and without respiratory gating.

Jelena Bock, Johannes Töger, Sebastian Bidhult, Karin Markenroth Bloch, Per Arvidsson, Mikael Kanski, Håkan Arheden, Frederik Testud, Andreas Greiser, Einar Heiberg and 1 more

Abstract readValidation Study
In one paragraph

Article in Acta radiologica (Stockholm, Sweden : 1987), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Hemodynamic forces from 4D flow magnetic resonance imaging predict left ventricular remodeling following cardiac resynchronization therapy.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Article
  9. Article
  10. 4D Flow cardiovascular magnetic resonance consensus statement: 2023 update.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Review
  11. Article
  12. Repeatability and reproducibility of various 4D Flow MRI postprocessing software programs in a multi-software and multi-vendor cross-over comparison study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Article
  13. Comparison of 2D and 4D Flow MRI in Neonates Without General Anesthesia.Journal of magnetic resonance imaging : JMRI · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Quality Control for 4D Flow MR Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2022
    Article
  18. Article
  19. MVnet: automated time-resolved tracking of the mitral valve plane in CMR long-axis cine images with residual neural networks: a multi-center, multi-vendor study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jelena Bock1 Department of Clinical Sciences, Lund University, Clinical Physiology, Skåne University Hospital, Lund, Sweden.
Johannes Töger1 Department of Clinical Sciences, Lund University, Clinical Physiology, Skåne University Hospital, Lund, Sweden.
Sebastian Bidhult1 Department of Clinical Sciences, Lund University, Clinical Physiology, Skåne University Hospital, Lund, Sweden.
Karin Markenroth Bloch4 Philips Healthcare, Lund, Sweden.ORCID https://orcid.org/0000-0002-3310-6667
Per Arvidsson1 Department of Clinical Sciences, Lund University, Clinical Physiology, Skåne University Hospital, Lund, Sweden.
Mikael Kanski1 Department of Clinical Sciences, Lund University, Clinical Physiology, Skåne University Hospital, Lund, Sweden.ORCID https://orcid.org/0000-0002-2909-8510
Håkan Arheden1 Department of Clinical Sciences, Lund University, Clinical Physiology, Skåne University Hospital, Lund, Sweden.
Frederik Testud6 Siemens Healthcare AB, Malmö, Sweden.ORCID https://orcid.org/0000-0003-4438-6227
Andreas Greiser7 Siemens Healthcare GmbH, Erlangen, Germany.
Einar Heiberg1 Department of Clinical Sciences, Lund University, Clinical Physiology, Skåne University Hospital, Lund, Sweden.
Marcus Carlsson1 Department of Clinical Sciences, Lund University, Clinical Physiology, Skåne University Hospital, Lund, Sweden.ORCID https://orcid.org/0000-0002-9480-5250

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background4D-flow magnetic resonance imaging (MRI) is increasingly used. PURPOSE: To validate 4D-flow sequences in phantom and in vivo, comparing volume flow and kinetic energy (KE) head-to-head, with and without respiratory gating. MATERIAL AND

methodsAchieva dStream (Philips Healthcare) and MAGNETOM Aera (Siemens Healthcare) 1.5-T scanners were used. Phantom validation measured pulsatile, three-dimensional flow with 4D-flow MRI and laser particle imaging velocimetry (PIV) as reference standard. Ten healthy participants underwent three cardiac MRI examinations each, consisting of cine-imaging, 2D-flow (aorta, pulmonary artery), and 2 × 2 accelerated 4D-flow with (Resp+) and without (Resp-) respiratory gating. Examinations were acquired consecutively on both scanners and one examination repeated within two weeks. Volume flow in the great vessels was compared between 2D- and 4D-flow. KE were calculated for all time phases and voxels in the left ventricle.

resultsPhantom results showed high accuracy and precision for both scanners. In vivo, higher accuracy and precision ( P < 0.001) was found for volume flow for the Aera prototype with Resp+ (-3.7 ± 10.4 mL, r = 0.89) compared to the Achieva product sequence (-17.8 ± 18.6 mL, r = 0.56). 4D-flow Resp- on Aera had somewhat larger bias (-9.3 ± 9.6 mL, r = 0.90) compared to Resp+ ( P = 0.005). KE measurements showed larger differences between scanners on the same day compared to the same scanner at different days.

conclusionSequence-specific in vivo validation of 4D-flow is needed before clinical use. 4D-flow with the Aera prototype sequence with a clinically acceptable acquisition time (<10 min) showed acceptable bias in healthy controls to be considered for clinical use. Intra-individual KE comparisons should use the same sequence.

Indexed as

AdultBlood Flow VelocityCardiac Imaging TechniquesCardiovascular SystemFemaleHumansImage Processing, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingMalePhantoms, ImagingPulsatile FlowReproducibility of ResultsRespiratory-Gated Imaging Techniques4D-flowcardiac outputheart failurevalvular regurgitation

Identifiers

PMID30479136
PMCPMC6402051

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.