Evidence map›Paper›PMID 30479093›Full record

ArticleJournal of gynecologic oncology2019

Efficacy and dosimetry analysis of image-guided radioactive ¹²⁵I seed implantation as salvage treatment for pelvic recurrent cervical cancer after external beam radiotherapy.

Ang Qu, Ping Jiang, Haitao Sun, Weijuan Jiang, Yuliang Jiang, Suqing Tian, Junjie Wang

Open access · diamondAbstract read
In one paragraph

Article in Journal of gynecologic oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 40 citations in OpenAlex.

  1. Trial
  2. Article
  3. Local efficacy and safety of CT-guided Iodine-125 seed implantation in the treatment of recurrent malignant tumors: a retrospective study.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  4. Article
  5. Investigation into the efficiency and prognostic elements of CT-guided ¹²⁵I particle implantation for liver cancer.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Article
  6. Article
  7. Review
  8. Radiation oncology (London, England) · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Clinical efficacy of iodine-125 (American journal of cancer research · 2023
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ang QuDepartment of Radiation Oncology, Peking University Third Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-7169-1780
Ping JiangDepartment of Radiation Oncology, Peking University Third Hospital, Beijing, China.ORCID https://orcid.org/0000-0001-8820-489X
Haitao SunDepartment of Radiation Oncology, Peking University Third Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-7638-2063
Weijuan JiangDepartment of Radiation Oncology, Peking University Third Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-2429-7772
Yuliang JiangDepartment of Radiation Oncology, Peking University Third Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-2390-8973
Suqing TianDepartment of Radiation Oncology, Peking University Third Hospital, Beijing, China.ORCID https://orcid.org/0000-0003-3334-681X
Junjie WangDepartment of Radiation Oncology, Peking University Third Hospital, Beijing, China. junjiewang_edu@sina.cn.ORCID https://orcid.org/0000-0001-8269-1105
Peking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the efficacy of image-guided radioactive ¹²⁵I seed (IGRIS) implantation for pelvic recurrent cervical cancer (PRCC) after external beam radiotherapy (EBRT), and analyze the influence of clinical and dosimetric factors on efficacy.

methodsFrom July 2005 to October 2015, 36 patients with PRCC received IGRIS. We evaluated local progression-free survival (LPFS) and overall survival (OS).

resultsThe median follow up was 11.5 months. The 1- and 2-year LPFS rate was 34.9% and 20%, respectively. The multivariate analysis indicated recurrence site (central or pelvic wall) (hazard ratio [HR]=0.294; 95% confidence interval [CI]=0.121-0.718), lesion volume (HR=2.898; 95% CI=1.139-7.372),

conclusionIGRIS implantation could be a safe and effective salvage treatment for PRCC after EBRT, which could markedly release the pain. Recurrence site, tumor volume and dose were the main factors affected efficacy. Compared with central recurrence, it was more suitable for patients with pelvic wall recurrent cervical cancer after EBRT.

Indexed as

AdenocarcinomaAdultAgedAged, 80 and overBrachytherapyCarcinoma, Squamous CellDose-Response Relationship, RadiationFemaleHumansIodine RadioisotopesKaplan-Meier EstimateMiddle AgedNeoplasm Recurrence, LocalProgression-Free SurvivalProportional Hazards ModelsRadiotherapy, Image-GuidedIodine-125Iodine RadioisotopesBrachytherapyImage-Guided Radiation TherapyIodine-125Neoplasm RecurrenceRadiation DosimetryUterine Cervical Neoplasms

Identifiers

PMID30479093
PMCPMC6304405
OpenAlexW2898830100

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.