Evidence map›Paper›PMID 30479077›Full record

ArticleAllergy, asthma & immunology research2019

Adaptation and Validation of the Korean Version of the Urticaria Control Test and Its Correlation With Salivary Cortisone.

Ji Ho Lee, Yoon Ju Bae, So Hee Lee, Su Chin Kim, Hyun Young Lee, Ga Young Ban, Yoo Seob Shin, Hae Sim Park, Juergen Kratzsch, Young Min Ye

Open access · hybridAbstract read
In one paragraph

Article in Allergy, asthma & immunology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Salivary Immune and Endocrine Biomarkers in Skin and Mucocutaneous Diseases.Advances in experimental medicine and biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Ji Ho LeeDepartment of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
Yoon Ju BaeInstitute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University of Leipzig, Leipzig, Germany.
So Hee LeeDepartment of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.
Su Chin KimClinical Trial Center, Ajou University Medical Center, Suwon, Korea.
Hyun Young LeeClinical Trial Center, Ajou University Medical Center, Suwon, Korea.
Ga Young BanDepartment of Pulmonary, Allergy and Critical Care Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-7961-742X
Yoo Seob ShinDepartment of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.ORCID https://orcid.org/0000-0002-9855-3185
Hae Sim ParkDepartment of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.ORCID https://orcid.org/0000-0003-2614-0303
Juergen KratzschInstitute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University of Leipzig, Leipzig, Germany.
Young Min YeDepartment of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea. ye9007@ajou.ac.kr.ORCID https://orcid.org/0000-0002-7517-1715
Ajou University · KRHallym University · KRLeipzig University · DEYonsei University · KR

Funding

Ministry of Health and Welfare HI16C0992Novartis Korea
6 · The paper itself

Abstract

purposeFrequent changes in chronic urticaria (CU) activity over time can cause psychological stress, which also serves as a trigger of CU. To measure the control status of CU, the Urticaria Control Test (UCT) was developed in Germany. This study aimed to investigate the validity, reliability and responsiveness to changes in CU for the Korean version of the UCT (K-UCT) and its relation with salivary cortisol and cortisone levels.

methodsLinguistic adaptation of the UCT into Korean was conducted. A total of 96 CU patients were enrolled, and 80 of them completed the study. The K-UCT and other outcome scores for CU were measured and repeated after 4 weeks of treatment. Control status was classified by physicians into well-controlled, partly-controlled, and uncontrolled CU. Salivary cortisol and cortisone were measured by liquid chromatography-tandem mass spectrometry.

resultsExcellent internal consistency and intra-class reliability were obtained. Strong correlations between the K-UCT and disease severity, reflected in the Urticaria Activity Score (UAS)/global assessment of urticaria control by physicians/patient assessment of symptom severity/CU-specific quality of life were noted. K-UCT scores ≥12 were found to be optimal for determining well-controlled CU (sensitivity, 75.0%; specificity, 758%; area under the curve, 0.824). Perceived stress scale scores were significantly correlated with the UAS and the K-UCT. Salivary cortisone levels were significantly correlated with K-UCT (

conclusionsThis study demonstrated that the K-UCT can be a valid instrument with which to gauge CU control status in Korean patients. Further studies are needed to validate salivary cortisone as a biomarker for CU control.

Indexed as

Chronic urticariaKorealinguistic adaptationurticaria control testvalidation

Identifiers

PMID30479077
PMCPMC6267182
OpenAlexW2903415548

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.