Evidence map›Paper›PMID 30478606›Full record

ArticleExtremophiles : life under extreme conditions2019

Improved production of bacteriorhodopsin from Halobacterium salinarum through direct amino acid supplement in the basal medium.

C Jeganathan, K Thamaraiselvi, T C Sabari Girisun

Abstract read
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In one paragraph

Article in Extremophiles : life under extreme conditions, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

C JeganathanNanophotonics Laboratory, School of Physics, Bharathidasan University, Tiruchirappalli, 620 024, India.
K ThamaraiselviLaboratory of Molecular Bioremediation and Nanobiotechnology, Department of Environmental Biotechnology, School of Environmental Sciences, Bharathidasan University, Tiruchirappalli, 620 024, India.
T C Sabari GirisunNanophotonics Laboratory, School of Physics, Bharathidasan University, Tiruchirappalli, 620 024, India. sabarigirisun@bdu.ac.in.ORCID http://orcid.org/0000-0003-2208-0091
Bharathidasan University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enhanced production and growth of Halobacterium salinarum are achieved by direct supplement of essential amino acids in the modified nutrient culture medium. As arginine (R) and aspartate (D) are the main amino acid sources for producing bacteriorhodopsin efficiently from Halobacterium salinarum, both individual and combined effects of these two amino acids (in different compositions) in the basal medium were studied. The BR production is enhanced by 83% on the eighth day (saturated) for all individual and combined amino acid supplements. Maximum production of 201 mg/l is observed for combined amino acid (R3D2)-supplemented culture which is 4.46-fold higher than the conventional culture growth from the basal medium. The obtained results suggest the efficient method to enhance BR production at low cost and thus, open up the possibility to utilize this potential biomolecule for various photonics applications which were earlier restricted due to the high cost of protein molecules.

Indexed as

Amino AcidsBacteriorhodopsinsCosts and Cost AnalysisCulture MediaHalobacterium salinarumIndustrial MicrobiologyAmino AcidsBacteriorhodopsinsCulture MediaAmino acidArginine aspartateBacteriorhodopsinEnhanced BR production

Identifiers

PMID30478606
OpenAlexW2902501653

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.