ReviewUrolithiasis2019
Empiric therapy for kidney stones.
Review in Urolithiasis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 4 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- The causal relationship between 179 lipid species and urolithiasis: a bidirectional and multivariable Mendelian randomization study combined with meta-analysis.Lipids in health and disease · 2025Pooled it
- The suggested dosage and course of thiazide diuretics on preventing recurrent urolithiasis: an upstate meta-analysis.World journal of urology · 2025Pooled it
- Mendelian Randomization Analysis of Genetic Proxies of Thiazide Diuretics and the Reduction of Kidney Stone Risk.JAMA network open · 2023Pooled it
- Use of thiazide diuretics for the prevention of recurrent kidney calculi: a systematic review and meta-analysis.Journal of translational medicine · 2020Pooled it
- Urinary Supersaturation in a Randomized Trial Among Individuals With Recurrent Nephrolithiasis Comparing Empiric vs Selective Preventive Therapy: The URINE Trial.The Journal of urology · 2026Trial
- Baseline Urinary Calcium and the Efficacy of Thiazide Diuretics for Kidney Stone Prevention.The Journal of urology · 2026Article
- Characterizing Chemokine Signaling Pathways and Hub Genes in Calcium Oxalate-Induced Kidney Stone Formation: Insights from Rodent Models.Biochemical genetics · 2026Article
- Patient needs and preferences for a kidney stone self-monitoring app: a pilot survey analysis.Urolithiasis · 2026Article
- Association of Kidney Stone Disease With Metabolic Dysfunction Associated Liver Disease and Metabolic Dysfunction Associated Steatohepatitis: A National Inpatient Sample Study.JGH open : an open access journal of gastroenterology and hepatology · 2025Article
- Causal Relationships Between Dietary Habits, Gut Microbiota, Metabolites, Serum Proteins and Laboratory Biomarkers in Kidney Stone Formation: A Mendelian Randomisation Study.Journal of cellular and molecular medicine · 2025Article
- Cardiovascular and Renal Outcomes Following Repeated Naringenin Exposure in Normotensive and Hypertensive Rats.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Edaravone mitigates calcium oxalate-induced renal tubular epithelial cell injury by inhibiting autophagy-mediated ferroptosis.Naunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Healthy dietary patterns, biological aging, and kidney stones: evidence from NHANES 2007-2018.Frontiers in nutrition · 2025Article
- Development and validation of a predictive model for double-J stent encrustation after upper urinary tract calculi surgery.Urolithiasis · 2024Article
- Drivers of calcium oxalate stone formation in the octogenarian population.World journal of urology · 2023Article
- Kidney stones and thiazide diuretics: revisiting old assumptions in light of the NOSTONE trial.Clinical kidney journal · 2023Article
- Effect of a high-citrate beverage on urine chemistry in patients with calcium kidney stones.Urolithiasis · 2023Article
- Breaking the Cycle of Recurrent Calcium Stone Disease.Advances in kidney disease and health · 2023Review
- Curcumin alleviated oxidation stress injury by mediating osteopontin in nephrolithiasis rats.Acta cirurgica brasileira · 2023Article
- Surgical outcomes and postoperative hemorrhage risk of percutaneous nephrolithotomy (PCNL) for deer horn shaped stones analyzed by Lasso regression.American journal of translational research · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Careful phenotyping of patients to classify those with kidney stones has a long and important history in revealing the chemical basis for stone formation. Advances in our genetic understanding of kidney stones will lead to incredible insights regarding the pathophysiology of this common disorder. At this time, both evaluation of urine chemistry and genotyping of patients are extremely useful in the setting of a university and research-based kidney stone clinic. For much of the world, in a more clinically focused setting, these techniques are neither available nor absolutely necessary. Careful implementation of an empiric prescription based on stone composition would have an important effect to reduce stone recurrence in the world's many stone formers. Increased fluid intake, generic dietary manipulations, and prescription of potassium citrate and thiazides are all appropriate empiric therapies for people with calcium and uric acid kidney stones.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.