ArticleNature materials2019
Highly mechanosensitive ion channels from graphene-embedded crown ethers.
Article in Nature materials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 129 citations in OpenAlex.
- Conjugated Macrocycles for Host-Guest Recognition and Optoelectronic Applications.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Ion-electron coupling-enabled mechanical ion transistor with ultralow subthreshold swing.Science advances · 2026Article
- Leveraging Electrochemical Diversity in Engineering Liquid-State Ionic Devices for Neuromorphic Computing.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Synthesis and host-guest chemistry of a thiophene-extended pillar[6]arene: toward applications in nitroaromatics removal and cell imaging.Frontiers in chemistry · 2026Article
- Diffusive to Barrier-Limited Transition in the Aqueous Ion Transport through Nanoporous 2D Materials.The journal of physical chemistry. B · 2025Article
- Article
- Fast water transport and ionic sieving in ultrathin stacked nanoporous 2D membranes.National science review · 2025Article
- Oleophobic nanopore in graphene membrane enhances COJournal of molecular modeling · 2025Article
- Quasi-vertically asymmetric channels of graphene oxide membrane for ultrafast ion sieving.Nature communications · 2025Article
- Synaptic-like plasticity in 2D nanofluidic memristor from competitive bicationic transport.Science advances · 2024Article
- Molecular dynamics simulations reveal concentration-dependent blockage of graphene quantum dots to water channel protein openings.Scientific reports · 2024Article
- A Bioinspired Membrane with Ultrahigh LiAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Perfect confinement of crown ethers in MOF membrane for complete dehydration and fast transport of monovalent ions.Science advances · 2024Article
- Covalent Benzenesulfonic Functionalization of a Graphene Nanopore for Enhanced and Selective Proton Transport.The journal of physical chemistry. C, Nanomaterials and interfaces · 2024Article
- Memristive Response and Capacitive Spiking in Aqueous Ion Transport through Two-Dimensional Nanopore Arrays.The journal of physical chemistry letters · 2024Article
- Designing artificial ion channels with strict KNational science review · 2023Article
- Scaling of ionic conductance in a fluctuating single-layer nanoporous membrane.Scientific reports · 2023Article
- Fluids and Electrolytes under Confinement in Single-Digit Nanopores.Chemical reviews · 2023Review
- Stress induced delamination of suspended MoSPhysical chemistry chemical physics : PCCP · 2022Article
- Nonlinear electrohydrodynamic ion transport in graphene nanopores.Science advances · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ability to tune ionic permeation across nanoscale pores profoundly impacts diverse fields from nanofluidic computing to drug delivery. Here, we take advantage of complex formation between crown ethers and dissolved metal ions to demonstrate graphene-based ion channels highly sensitive to externally applied lattice strain. We perform extensive room-temperature molecular dynamics simulations of the effects of tensile lattice strain on ion permeation across graphene-embedded crown ether pores. Our findings suggest the first instance of solid-state ion channels with an exponential permeation sensitivity to strain, yielding an order of magnitude ion current increase for 2% of isotropic lattice strain. Significant permeation tuning is also shown to be achievable with anisotropic strains. Finally, we demonstrate strain-controllable ion sieving in salt mixtures. The observed high mechanosensitivity is shown to arise from strain-induced control over the competition between ion-crown and ion-solvent interactions, mediated by the atomic thinness of graphene.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.