Evidence map›Paper›PMID 30478388›Full record

ArticleNature microbiology2018

The interferon-inducible isoform of NCOA7 inhibits endosome-mediated viral entry.

Tomas Doyle, Olivier Moncorgé, Boris Bonaventure, Darja Pollpeter, Marion Lussignol, Marine Tauziet, Luis Apolonia, Maria-Teresa Catanese, Caroline Goujon, Michael H Malim

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Nature microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 66 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 1 synthesis or guideline pooled it, 92 citations in OpenAlex.

  1. Pooled it
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  13. Human MX1 orchestrates the cytoplasmic sequestration of neosynthesized influenza A virus vRNPs.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  14. Altered histone modifications inbioRxiv : the preprint server for biology · 2025
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Tomas DoyleDepartment of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK.
Olivier MoncorgéIRIM, CNRS, Université de Montpellier, Montpellier, France.
Boris BonaventureIRIM, CNRS, Université de Montpellier, Montpellier, France.
Darja PollpeterDepartment of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK.ORCID http://orcid.org/0000-0001-7602-3215
Marion LussignolDepartment of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK.
Marine TauzietIRIM, CNRS, Université de Montpellier, Montpellier, France.
Luis ApoloniaDepartment of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK.ORCID http://orcid.org/0000-0002-9451-6117
Maria-Teresa CataneseDepartment of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK.
Caroline GoujonIRIM, CNRS, Université de Montpellier, Montpellier, France. caroline.goujon@irim.cnrs.fr.ORCID http://orcid.org/0000-0001-8571-1108
Michael H MalimDepartment of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK. michael.malim@kcl.ac.uk.ORCID http://orcid.org/0000-0002-7699-2064
King's College London · GBCentre National de la Recherche Scientifique · FR

Funding

A Systems-level Approach to Studying HIV/AIDS Susceptibility and Substance AbuseR01DA033773 · NIDA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WOLINSKY, STEVEN M · 2012 to 2016
$4.6M
Medical Research Council G1000196NIDA NIH HHS R01 DA033773Wellcome Trust
6 · The paper itself

Abstract

Interferons (IFNs) mediate cellular defence against viral pathogens by upregulation of IFN-stimulated genes whose products interact with viral components or alter cellular physiology to suppress viral replication

Indexed as

A549 CellsAnimalsCell LineEndosomesGene Expression RegulationGene Knockout TechniquesHEK293 CellsHost-Pathogen InteractionsHumansInfluenza A virusInterferonsLysosomesMembrane ProteinsNuclear Receptor CoactivatorsProtein IsoformsProteolysisIFITM3 protein, humanInterferonsMembrane ProteinsNCOA7 protein, humanNuclear Receptor CoactivatorsProtein IsoformsRNA-Binding ProteinsVacuolar Proton-Translocating ATPases

Identifiers

PMID30478388
PMCPMC6329445
OpenAlexW2900729906

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.