Evidence map›Paper›PMID 30478321›Full record

ReviewNature methods2018

Acoustic tweezers for the life sciences.

Adem Ozcelik, Joseph Rufo, Feng Guo, Yuyang Gu, Peng Li, James Lata, Tony Jun Huang

Abstract readReview
In one paragraph

Review in Nature methods, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 252 papers.

0numbers the graph read from it
0cells of the map it votes in
252citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

252 citing papers in PubMed.

  1. Article
  2. Passive Metasurface Tweezers for Multi-Scale Orbital Transport and Trapping on Elastic Plates.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. CAMP: Closed-Loop Acoustic-Magnetic Propulsion of Microrobots for Precision Cell Manipulation.Advanced intelligent systems (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  18. Article
  19. Article
  20. Article

192 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adem OzcelikDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, USA.ORCID http://orcid.org/0000-0002-3124-795X
Joseph RufoDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, USA.
Feng GuoDepartment of Engineering Science and Mechanics, Pennsylvania State University, University Park, PA, USA.
Yuyang GuDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, USA.
Peng LiDepartment of Engineering Science and Mechanics, Pennsylvania State University, University Park, PA, USA.
James LataDepartment of Engineering Science and Mechanics, Pennsylvania State University, University Park, PA, USA.
Tony Jun HuangDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, USA. tony.huang@duke.edu.ORCID http://orcid.org/0000-0003-1205-3313

Funding

Extracellular vesicles and their ncRNA cargo as markers of trophoblast injuryR01HD086325 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI SADOVSKY, YOEL · 2015 to 2019
$3.6M
Single-Cell VirologyR01AI120560 · NIAID · PENNSYLVANIA STATE UNIVERSITY, THE · PI CAMERON, CRAIG E., HUANG, TONY JUN · 2015 to 2017
$1.4M
Determining treatment sensitivity in B cell lymphoma by novel microfluidics-based NK cell immunogenicity platformR33CA223908 · NCI · NORTHEASTERN UNIVERSITY · PI EVENS, ANDREW M, HUANG, TONY JUN · 2018 to 2020
$1.2M
NCI NIH HHS R33 CA223908NIAID NIH HHS R01 AI120560NICHD NIH HHS R01 HD086325
6 · The paper itself

Abstract

Acoustic tweezers are a versatile set of tools that use sound waves to manipulate bioparticles ranging from nanometer-sized extracellular vesicles to millimeter-sized multicellular organisms. Over the past several decades, the capabilities of acoustic tweezers have expanded from simplistic particle trapping to precise rotation and translation of cells and organisms in three dimensions. Recent advances have led to reconfigured acoustic tweezers that are capable of separating, enriching, and patterning bioparticles in complex solutions. Here, we review the history and fundamentals of acoustic-tweezer technology and summarize recent breakthroughs.

Indexed as

AcousticsBiological Science DisciplinesModels, BiologicalAnimalsHumansOptical Tweezers

Identifiers

PMID30478321
PMCPMC6314293

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.