ArticleScientific reports2018
Treatment outcome and associated factors among patients with epilepsy.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 3 of them syntheses that pooled it.
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Who cites it
38 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Treatment outcome and its predictors among children with epilepsy on chronic follow-up in Ethiopia: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Prevalence, incidence, and trends of epilepsy among children and adolescents in Africa: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Treatment Outcome of Epileptic Patients Receiving Antiepileptic Drugs in Ethiopia: A Systematic Review and Meta-Analysis.Behavioural neurology · 2021Pooled it
- Epilepsy Treatment Outcome and Associated Factors in Children and Adolescents in a Resource-limited Setting: A Retrospective Cohort Study.Clinical medicine insights. Pediatrics · 2026Article
- Health-related quality of life and associated factors among patients living with epilepsy of Mekelle City Hospitals, Northern Ethiopia: a multicenter observational study.Health and quality of life outcomes · 2026Observational
- Treatment outcomes and associated factors among children with epilepsy attending the pediatric follow-up clinic at Hiwot Fana Comprehensive Specialized Hospital.BMC pediatrics · 2025Article
- Prevalence and determinants of uncontrolled seizures in adult people with epilepsy attending comprehensive specialized hospitals in Northwest Amhara, Ethiopia: a multicenter study.BMC public health · 2025Article
- Observational
- The Role of Artificial Intelligence in the Diagnosis and Management of Non-convulsive Seizures: A Narrative Review.Cureus · 2025Review
- A Real-Time Epilepsy Detection Method Using Embedded Zero Tree Wavelet Approach and Support Vector Machine.Behavioural neurology · 2025Article
- Current Role of Brivaracetam in the Management of Epilepsy in Adults and Children: A Systematic Review.Cureus · 2024Review
- Research hotspots and frontiers of alcohol and epilepsy: A bibliometric analysis.Neuropsychopharmacology reports · 2024Review
- Tailoring epilepsy treatment: personalized micro-physiological systems illuminate individual drug responses.Annals of medicine and surgery (2012) · 2024Review
- The Role of Pharmacists' Interventions in Increasing Medication Adherence of Patients With Epilepsy: A Scoping Review.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2024Article
- Effect of Mobile Health Applications on Improving Self-Management Knowledge and Seizure Control in Epilepsy Patients: A Scoping Review.Healthcare informatics research · 2024Article
- Adherence to Epilepsy's Medical Recommendations.Brain sciences · 2024Article
- Risk Assessment Tool in Predicting the Therapeutic Outcomes of Antiseizure Medication in Adults with Epilepsy.Therapeutics and clinical risk management · 2024Article
- Observational
- Epilepsy Treatment Outcome and Its Predictors Among Children Who Had Chronic Follow Up at Dessie Comprehensive Specialized Hospital.Patient related outcome measures · 2024Article
- Clinical and economic implications of epilepsy management across treatment lines in Spain: a real-life database analysis.Journal of neurology · 2023Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epilepsy is a major public health problem worldwide. Despite multiple drug therapies, people with epilepsy continue to have frequent seizures. There is a dearth of data on epilepsy treatment outcome and associated factors in our setting. Therefore, the aim of this was to assess treatment outcome and associated factors among epileptic patients on follow up at the neurologic clinic of Ayder comprehensive specialized hospital, Ethiopia. A cross-sectional study was conducted on randomly selected epileptic patients. Data were collected through patient interview and review of medical records. Epilepsy treatment outcome was evaluated in terms of seizure control status in the last one year follow up period. Binary logistic regression analysis was performed to identify predictors of treatment outcome. A total of 270 patients were included. Of whom, 46.6% had controlled seizures. Whereas, 38.5%, 8.8%, and 5.9% had experienced seizure attacks 1-5 times, 6-10 times, and greater than 10 times, respectively. Alcohol consumption [adjusted odds ratio [(AOR): 14.87, 95% confidence interval (CI): 3.25-68.11], negative medication belief [AOR: 3.0, 95%CI: 1.31-6.71], low medication adherence [AOR:11.52, 95%CI: 3.25-40.82], and presence of comorbidities [AOR: 10.35, 95%CI: 4.40-24.40] were predictors of uncontrolled seizure. Our finding revealed that more than half of the epileptic patients had uncontrolled seizure. Epileptic patients with a negative medication belief, comorbidities, low medication adherence, and those who consume alcohol were more likely to have uncontrolled seizure. Therefore, more emphasis should be given to these patients.
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