Evidence map›Paper›PMID 30478248›Full record

ArticleGenes & development2018

Phosphorylation by the stress-activated MAPK Slt2 down-regulates the yeast TOR complex 2.

Kristin L Leskoske, Françoise M Roelants, Anita Emmerstorfer-Augustin, Christoph M Augustin, Edward P Si, Jennifer M Hill, Jeremy Thorner

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Making PI3K superfamily enzymes run faster.Advances in biological regulation · 2025
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Heme Oxygenase/Carbon Monoxide Participates in the Regulation ofInternational journal of molecular sciences · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Substrates of the MAPK Slt2: Shaping Yeast Cell Integrity.Journal of fungi (Basel, Switzerland) · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Analysis of the roles of phosphatidylinositol-4,5-Molecular biology of the cell · 2019
    Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kristin L LeskoskeDepartment of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA.
Françoise M RoelantsDepartment of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA.
Anita Emmerstorfer-AugustinDepartment of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA.
Christoph M AugustinDepartment of Mechanical Engineering, University of California at Berkeley, Berkeley, California 94720, USA.
Edward P SiDepartment of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA.
Jennifer M HillDepartment of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA.
Jeremy ThornerDepartment of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA.ORCID 0000-0002-2583-500X
University of California, Berkeley · US

Funding

THE MOLECULAR BASIS OF CELL FUNCTIONT32GM007232 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BILDER, DAVID, UNAL, ELCIN · 1985 to 2022
$36.4M
Yeast Protein Kinase Signaling Networks: Specificity, Regulation and FunctionR01GM021841 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI THORNER, JEREMY W. · 1985 to 2019
$11.8M
A Zeiss Elyra S1 Structured Illumination Microscope for the Biological Imaging FaS10OD018136 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI RUZIN, STEVEN EARL · 2014 to 2014
$600k
NIGMS NIH HHS R01 GM021841NIGMS NIH HHS T32 GM007232NIH HHS S10 OD018136
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Down-RegulationAcetic AcidCarrier ProteinsCell MembraneEnzyme ActivationFatty Acids, MonounsaturatedGene DeletionGlycogen Synthase Kinase 3Mechanistic Target of Rapamycin Complex 2Mitogen-Activated Protein KinasesPhosphorylationSaccharomyces cerevisiae ProteinsSignal TransductionStress, PhysiologicalAcetic AcidAvo2 protein, S cerevisiaeCarrier ProteinsFatty Acids, MonounsaturatedGlycogen Synthase Kinase 3MCK1 protein, S cerevisiaeMechanistic Target of Rapamycin Complex 2Mitogen-Activated Protein KinasesSaccharomyces cerevisiae ProteinsSLT2 protein, S cerevisiaethermozymocidinmutantsprotein kinaseregulationsignal transductionyeast

Identifiers

PMID30478248
PMCPMC6295167
OpenAlexW2902240097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.