Evidence map›Paper›PMID 30478231›Full record

ArticleApplied and environmental microbiology2019

1,4,7-Triazacyclononane Restores the Activity of β-Lactam Antibiotics against Metallo-β-Lactamase-Producing

Anou M Somboro, Daniel G Amoako, John Osei Sekyere, Hezekiel M Kumalo, René Khan, Linda A Bester, Sabiha Y Essack

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Identification of Potential Inhibitors of Three NDM Variants ofCurrent computer-aided drug design · 2025
    Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Metallo-ß-lactamases: a review.Molecular biology reports · 2020
    Review
  12. Review
  13. Genomic Analysis of CarbapenemaseMicroorganisms · 2020
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anou M SomboroAntimicrobial Research Unit, School of Health Sciences, University of KwaZulu-Natal, Durban, South Africa anou.somboro@gmail.com.ORCID 0000-0002-1085-7740
Daniel G AmoakoAntimicrobial Research Unit, School of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.ORCID 0000-0003-3551-3458
John Osei SekyereDepartment of Medical Microbiology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.ORCID 0000-0002-9508-984X
Hezekiel M KumaloDiscipline of Medical Biochemistry, School of Laboratory Medicine and Medical Science, University of KwaZulu-Natal, Durban, South Africa.
René KhanDiscipline of Medical Biochemistry, School of Laboratory Medicine and Medical Science, University of KwaZulu-Natal, Durban, South Africa.
Linda A BesterBiomedical Resource Unit, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
Sabiha Y EssackAntimicrobial Research Unit, School of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
University of KwaZulu-Natal · ZAUniversity of Pretoria · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metallo-β-lactamase (MBL)-producing

Indexed as

Anti-Bacterial Agentsbeta-Lactamase Inhibitorsbeta-Lactamasesbeta-LactamsEnterobacteriaceaeEnterobacteriaceae InfectionsHeterocyclic CompoundsHumansMicrobial Sensitivity Tests1,4,7-triazacyclononaneAnti-Bacterial Agentsbeta-Lactamase Inhibitorsbeta-Lactamasesbeta-LactamsHeterocyclic Compoundsbinding affinityEnterobacteriaceaemetallo-β-lactamase inhibitorTACNβ-lactams

Identifiers

PMID30478231
PMCPMC6344617
OpenAlexW2903409786

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.