ArticleJournal of bacteriology2019
DksA Controls the Response of the Lyme Disease Spirochete
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In one paragraph
Article in Journal of bacteriology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 26 citations in OpenAlex.
- Metabolic regulation of the carbonyl stress pathway and methylglyoxal in Lyme disease and relapsing fever spirochetes.PLoS pathogens · 2026Article
- Transcription regulator TrtA modulates oxygen stress response inApplied and environmental microbiology · 2025Article
- Dissection of amino acid acquisition pathways demonstrates that amino acid starvation of Borrelia burgdorferi results in a (p)ppGpp-independent maladaptive response.Communications biology · 2025Article
- Virulence Regulation inMicroorganisms · 2025Review
- Article
- Article
- Hitchhiker's Guide toJournal of bacteriology · 2024Review
- Pathogenicity and virulence ofVirulence · 2023Review
- Review
- The glycerol-3-phosphate dehydrogenases GpsA and GlpD constitute the oxidoreductive metabolic linchpin for Lyme disease spirochete host infectivity and persistence in the tick.PLoS pathogens · 2022Article
- Deletion of a Genetic Region of lp17 Affects Plasmid Copy Number inFrontiers in cellular and infection microbiology · 2022Article
- Virus-Host Interaction GetsInternational journal of molecular sciences · 2021Article
- Interactions between Borrelia burgdorferi and its hosts across the enzootic cycle.Parasite immunology · 2021Review
- DksA-dependent regulation of RpoS contributes to Borrelia burgdorferi tick-borne transmission and mammalian infectivity.PLoS pathogens · 2021Article
- Gene Regulation and Transcriptomics.Current issues in molecular biology · 2021Article
- Interactions Between Ticks and Lyme Disease Spirochetes.Current issues in molecular biology · 2021Article
- YebC regulates variable surface antigen VlsE expression and is required for host immune evasion in Borrelia burgdorferi.PLoS pathogens · 2020Article
- DksA plays an essential role in regulating the virulence of Borrelia burgdorferi.Molecular microbiology · 2020Article
- Lyme Disease Frontiers: ReconcilingPathogens (Basel, Switzerland) · 2019Review
- Generality of Post-Antimicrobial Treatment Persistence ofInfection and immunity · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 1 country.
William K BoyleDepartment of Medical Microbiology and Immunology, Creighton University, Omaha, Nebraska, USA.
Ashley M GroshongDepartment of Medicine, UConn Health, Farmington, Connecticut, USA.
Dan DrecktrahDivision of Biological Sciences, University of Montana, Missoula, Montana, USA.
Julie A BoylanLaboratory of Bacteriology, Gene Regulation Section, Division of Intramural Research, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA.
Frank C GherardiniLaboratory of Bacteriology, Gene Regulation Section, Division of Intramural Research, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA.
Jon S BlevinsDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
D Scott SamuelsDivision of Biological Sciences, University of Montana, Missoula, Montana, USA.
Travis J BourretDepartment of Medical Microbiology and Immunology, Creighton University, Omaha, Nebraska, USA TravisBourret@creighton.edu.ORCID 0000-0002-4154-929X
National Institutes of Health · USUniversity of Montana · USCHI Health Creighton University Medical Center - Bergan Mercy · USUConn Health · USUniversity of Arkansas for Medical Sciences · US
Funding
UNMC Structural Biology CoreP20GM103427 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI PAUL L SORGEN · 2012 to 2026
$59.2MZINC FINGER-INSPIRED FLUORESCENT CHEMOSENSORSP20RR016469 · NCRR · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI EUDY, JAMES D · 2001 to 2011
$36.2MStudy of the Cell-specific Inflammasome Responses During Defense Against Gram-negative BacteriaP20GM103625 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI SMELTZER, MARK S · 2012 to 2021
$21.5MThe Roles of Key Transcription Factors on the Pathogenesis of B. Burgdorferi, the Causative Agent of Lyme DiseaseZIAAI000905 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI GHERARDINI, FRANK · 2009 to 2023
$12.4MPilot Grant ProgramP30GM145393 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI MARK S SMELTZER · 2022 to 2026
$7.6MRegulation of Gene Expression in Borrelia burgdorferiR01AI051486 · NIAID · UNIVERSITY OF MONTANA · PI SAMUELS, D. SCOTT · 2003 to 2018
$5.1MRpoS-mediated virulence regulation in Borrelia burgdorferiR01AI087678 · NIAID · UNIV OF ARKANSAS FOR MED SCIS · PI BLEVINS, JON SCOTT · 2010 to 2014
$1.8MRrp2-dependent gene regulation in Borrelia burgdorferiR21AI119532 · NIAID · UNIV OF ARKANSAS FOR MED SCIS · PI BLEVINS, JON SCOTT · 2015 to 2016
$403kIntegrated Phosphor and Fluorescence Imager (Typhoon FLA9500)S10OD021710 · OD · UNIVERSITY OF MONTANA · PI NUNBERG, JACK H · 2016 to 2016
$138kNCRR NIH HHS P20 RR016469NIAID NIH HHS R01 AI051486NIAID NIH HHS R01 AI087678NIAID NIH HHS R21 AI119532NIGMS NIH HHS P20 GM103427NIGMS NIH HHS P20 GM103625NIGMS NIH HHS P30 GM145393NIH HHS S10 OD021710
Abstract
The pathogenic spirochete
Indexed as
Gene Expression Regulation, BacterialStress, PhysiologicalAdaptation, PhysiologicalBacterial ProteinsBorrelia burgdorferiColony Count, MicrobialCulture MediaGene DeletionGene Expression ProfilingGuanosine PentaphosphateGuanosine TetraphosphateMicroarray AnalysisMicrobial ViabilityRegulonTranscription FactorsBacterial ProteinsCulture MediaGuanosine PentaphosphateGuanosine TetraphosphateTranscription FactorsBorrelia burgdorferiDksAgene expressionglobal regulatory networksLyme diseasestringent response
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.