Evidence map›Paper›PMID 30478083›Full record

ArticleJournal of bacteriology2019

The Core and Holoenzyme Forms of RNA Polymerase from

Tomáš Kouba, Jiří Pospíšil, Jarmila Hnilicová, Hana Šanderová, Ivan Barvík, Libor Krásný

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

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  14. A majority ofProceedings of the National Academy of Sciences of the United States of America · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Tomáš KoubaMRC Laboratory of Molecular Biology, Cambridge, United Kingdom tkouba@embl.fr krasny@biomed.cas.cz.
Jiří PospíšilLaboratory of Microbial Genetics and Gene Expression, Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
Jarmila HnilicováLaboratory of Microbial Genetics and Gene Expression, Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
Hana ŠanderováLaboratory of Microbial Genetics and Gene Expression, Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
Ivan BarvíkDivision of Biomolecular Physics, Institute of Physics, Faculty of Mathematics and Physics, Charles University in Prague, Prague, Czech Republic.
Libor KrásnýLaboratory of Microbial Genetics and Gene Expression, Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic tkouba@embl.fr krasny@biomed.cas.cz.ORCID 0000-0002-4120-4347
Czech Academy of Sciences, Institute of Microbiology · CZCharles University · CZMRC Laboratory of Molecular Biology · GB

Funding

Medical Research Council MC_EX_G0901534
6 · The paper itself

Abstract

Bacterial RNA polymerase (RNAP) is essential for gene expression and as such is a valid drug target. Hence, it is imperative to know its structure and dynamics. Here, we present two as-yet-unreported forms of

Indexed as

Cryoelectron MicroscopyDNA-Directed RNA PolymerasesHoloenzymesMycobacterium smegmatisProtein ConformationDNA-Directed RNA PolymerasesHoloenzymesbacterial transcriptionconformational changecryo-electron microscopymycobacteriaprotein structureRNA polymerasetranscription initiation factor

Identifiers

PMID30478083
PMCPMC6351736
OpenAlexW2902260841

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.