Evidence map›Paper›PMID 30478032›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

α

Tracy L Fetterly, Aakash Basu, Brett P Nabit, Elias Awad, Kellie M Williford, Samuel W Centanni, Robert T Matthews, Yuval Silberman, Danny G Winder

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Synaptic Effects Induced by Alcohol.Current topics in behavioral neurosciences · 2025
    Review
  7. Neural Circuitries and Alcohol Use Disorder: Cutting Corners in the Cycle.Current topics in behavioral neurosciences · 2025
    Review
  8. Article
  9. Thalamocortical mGlu8 Modulates Dorsal Thalamus Excitatory Transmission and Sensorimotor Activity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  10. Article
  11. Review
  12. An ensemble recruited by αNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Article
  13. BNST PKCδ neurons are activated by specific aversive conditions to promote anxiety-like behavior.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Article
  14. Noradrenergic stimulation of αScientific reports · 2023
    Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Tracy L FetterlyVanderbilt Center for Addiction Research.
Aakash BasuVanderbilt Center for Addiction Research.
Brett P NabitDepartment of Molecular Physiology and Biophysics.ORCID 0000-0001-9459-2462
Elias AwadDepartment of Molecular Physiology and Biophysics.
Kellie M WillifordVanderbilt Center for Addiction Research.
Samuel W CentanniVanderbilt Center for Addiction Research.ORCID 0000-0002-3941-7677
Robert T MatthewsVanderbilt Center for Addiction Research.ORCID 0000-0002-1235-3802
Yuval SilbermanDepartment of Molecular Physiology and Biophysics, yus72@psu.edu danny.winder@vanderbilt.edu.
Danny G WinderVanderbilt Center for Addiction Research, yus72@psu.edu danny.winder@vanderbilt.edu.
Allen Institute for Brain Science · USInstitute of Molecular Biology and Biophysics · RUVanderbilt Psychiatric Hospital · USPennsylvania State University · US

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Vanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALVIN C POWERS · 2012 to 2026
$29.3M
Shop Module CoreP30EY008126 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI David J. Calkins · 1989 to 2026
$19.6M
Vanderbilt Mouse Metabolic Physiology CenterU24DK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2001 to 2015
$14.9M
TRAINING IN PHARMACOLOGICAL SCIENCEST32GM007628 · NIGMS · VANDERBILT UNIVERSITY · PI BARNETT, JOEY VICTOR, KAVALALI, EGE T · 1985 to 2022
$11.2M
Vanderbilt/Meharry Initiative for Minority Student DvptR25GM062459 · NIGMS · VANDERBILT UNIVERSITY · PI VELEZ EDWARDS, DIGNA R · 2002 to 2020
$10.4M
Training in Fundamental NeuroscienceT32MH064913 · NIMH · VANDERBILT UNIVERSITY · PI IHRIE, REBECCA A, WINDER, DANNY G. · 2001 to 2022
$7.6M
Research Project: Sensory and Multisensory Contributions to AutismU54HD083211 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DYKENS, ELISABETH MAY · 2015 to 2019
$7.1M
Vanderbilt Mouse Metabolic Phenotyping CenterU2CDK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2016 to 2021
$6.3M
Sex Dependent Recruitment of PKCdelta Neurons by Stress: Administrative Supplement for Noradrenergic Regulation in the BNSTR01DA042475 · NIDA · VANDERBILT UNIVERSITY · PI WINDER, DANNY G. · 2016 to 2025
$4.0M
Alcohol action on extended amygdala glutamate synapsesR37AA019455 · NIAAA · VANDERBILT UNIVERSITY · PI WINDER, DANNY G. · 2015 to 2024
$3.9M
NCI NIH HHS P30 CA068485NEI NIH HHS P30 EY008126NIAAA NIH HHS R00 AA022937NIAAA NIH HHS R37 AA019455NICHD NIH HHS U54 HD083211NIDA NIH HHS R01 DA042475NIDDK NIH HHS P30 DK020593NIDDK NIH HHS P30 DK058404NIDDK NIH HHS U24 DK059637NIDDK NIH HHS U2C DK059637NIGMS NIH HHS R25 GM062459NIGMS NIH HHS T32 GM007628NIMH NIH HHS T32 MH064913
6 · The paper itself

Abstract

Stress contributes to numerous psychiatric disorders. Corticotropin releasing factor (CRF) signaling and CRF neurons in the bed nucleus of the stria terminalis (BNST) drive negative affective behaviors, thus agents that decrease activity of these cells may be of therapeutic interest. Here, we show that acute restraint stress increases cFos expression in CRF neurons in the mouse dorsal BNST, consistent with a role for these neurons in stress-related behaviors. We find that activation of α

Indexed as

Adrenergic alpha-2 Receptor AgonistsAnimalsCorticotropin-Releasing HormoneFemaleGene ExpressionGenes, fosGuanfacineMaleMiceMice, Inbred C57BLNeuronsNorepinephrineOvariectomyParabrachial NucleusPatch-Clamp TechniquesProtein Kinase C-deltaAdrenergic alpha-2 Receptor AgonistsCorticotropin-Releasing HormoneGuanfacineNorepinephrinePrkcd protein, mouseProtein Kinase C-deltaReceptors, Adrenergic, alpha-2Receptors, G-Protein-CoupledBNSTCRFnorepinephrineparabrachialstress

Identifiers

PMID30478032
PMCPMC6335747
OpenAlexW2902253857

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.