Evidence map›Paper›PMID 30477818›Full record

ArticleBurns : journal of the International Society for Burn Injuries2019

Burn injury and multiple sclerosis: A retrospective case-control study.

Matthew R McCann, William F Hill, Jinhui Yan, Sarah Rehou, Marc G Jeschke

Abstract read
In one paragraph

Article in Burns : journal of the International Society for Burn Injuries, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Matthew R McCannSunnybrook Research Institute, Toronto, Ontario, Canada.
William F HillSunnybrook Research Institute, Toronto, Ontario, Canada.
Jinhui YanFaculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Sarah RehouSunnybrook Research Institute, Toronto, Ontario, Canada; Ross Tilley Burn Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Marc G JeschkeSunnybrook Research Institute, Toronto, Ontario, Canada; Ross Tilley Burn Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; Division of Plastic and Reconstructive Surgery, Department of Surgery, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; Department of Immunology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. Electronic address: marc.jeschke@sunnybrook.ca.

Funding

Hepatic ER stress contributes to morbidity and mortality after burn injury.R01GM087285 · NIGMS · SUNNYBROOK & WOMEN'S COLL HLTH SCIS CTR · PI BOEHNING, DARREN F, JESCHKE, MARC GERHARD · 2010 to 2018
$1.9M
NIGMS NIH HHS R01 GM087285
6 · The paper itself

Abstract

objectivesThe purpose of this study was to determine whether having a previous diagnosis of multiple sclerosis (MS) changed acute care needs in burn-injured patients.

methodsThis was a retrospective case-control study that included adult (aged ≥18years) patients with an acute burn injury. Control patients were matched with eleven patients with a history of MS at a 4:1 ratio. Outcomes included fluid resuscitation volumes, temperature, heart rate, mean arterial pressure, in-hospital complications, and hospital length of stay (LOS).

resultsThere were fifty-five patients included and of those, eleven had a documented history of MS. Fluid resuscitation volumes, temperature, heart rate, and mean arterial pressure were similar between groups during the resuscitation period (p>0.05). LOS was similar between both groups (12, IQR: 2-17 vs. median 16, IQR: 12-21; p=0.090). However, when normalized to % TBSA burn, patients with MS had a significantly higher median LOS/% TBSA burned (1.2, IQR: 0.7-2.0 vs. 2.1, IQR: 1.1-7.1; p=0.031).

conclusionsPatients with concurrent burn injuries and MS have a significantly longer LOS/% TBSA burn suggesting that more time is required to heal their wounds. Surprisingly, there were no other significant differences in the after the burn acute phase between these two cohorts.

Indexed as

AdultArterial PressureBody Surface AreaBody TemperatureBurnsCase-Control StudiesComorbidityFemaleFluid TherapyHeart RateHumansLength of StayMaleMiddle AgedMultiple SclerosisResuscitationBurnsMultiple sclerosis

Identifiers

PMID30477818
PMCPMC6326880

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.