ArticleBMC research notes2018
Temporal trend of the proportion of patients presenting with advanced HIV in French Guiana: stuck on the asymptote?
Article in BMC research notes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 20 citations in OpenAlex.
- Evolution of HIV epidemic trends and diagnostic delays in French Guiana: how can we make further progress?BMC infectious diseases · 2026Article
- Forty Years of HIV Research in French Guiana: Comprehend to Combat.Pathogens (Basel, Switzerland) · 2024Review
- Pattern, causes and functional outcome of peripheral neuropathies in the Amazon region.PloS one · 2024Observational
- [Overview of infectious and non-infectious diseases in French Guiana in 2022].Medecine tropicale et sante internationale · 2023Review
- Establishing the proportion of severe/moderately severe vs mild cases of progressive disseminated histoplasmosis in patients with HIV.PLoS neglected tropical diseases · 2022Article
- Risk Factors for Mortality among HIV-Infected Patients with Disseminated Histoplasmosis.Journal of fungi (Basel, Switzerland) · 2020Article
- Temporal trends of cutaneo-mucous histoplasmosis in persons living with HIV in French Guiana: Early diagnosis defuses South American strain dermotropism.PLoS neglected tropical diseases · 2020Article
- Disseminated Histoplasmosis in HIV-Infected Patients: A Description of 34 Years of Clinical and Therapeutic Practice.Journal of fungi (Basel, Switzerland) · 2020Article
- Article
- Changes Over Time in the Proportion of Advanced HIV Disease in Two High HIV Prevalence Settings in Ndhiwa (Kenya) and Eshowe (South Africa).Journal of the International Association of Providers of AIDS CareArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIn French Guiana, the French territory with the most preoccupying HIV epidemic, there have been great efforts to intensify and diversify HIV testing strategies. The aim of the present study was to review the temporal trends of patients diagnosed with advanced HIV disease in French Guiana. Data trends from the HIV cohort of French Guiana between 1996 and 2016 were thus analyzed.
resultsThe proportion of patients diagnosed with advanced disease did not decline over time. Males had lower CD4 counts at the time of diagnosis and there was a plateau for both males (around 40%) and females (around 25%) with no apparent reduction of the proportion of advanced disease. Older age groups and migrants presented more often with advanced disease. By contrast, the proportion of patients diagnosed with stage B and C disease declined over time and the CD4 count at antiretroviral initiation and the CD4 nadir increased over time. Despite some progress, the group of patients with advanced disease reached a plateau around 30% suggesting this particular group still has epidemiological importance in driving the epidemic and in fueling morbidity and mortality, and thus remains a challenge for testing strategies.
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