Evidence map›Paper›PMID 30477539›Full record

ReviewGenome biology2018

Livestock 2.0 - genome editing for fitter, healthier, and more productive farmed animals.

Christine Tait-Burkard, Andrea Doeschl-Wilson, Mike J McGrew, Alan L Archibald, Helen M Sang, Ross D Houston, C Bruce Whitelaw, Mick Watson

Open access · goldAbstract readReview
In one paragraph

Review in Genome biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 159 citations in OpenAlex.

  1. Clinical outcome of an SCNT-derivedFrontiers in genome editing · 2026
    Article
  2. Editorial: Genome editing in poultry and livestock.Frontiers in genome editing · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Cardiac Xenotransplantation: A Narrative Review.Reviews in cardiovascular medicine · 2024
    Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. AgAnimalGenomes: browsers for viewing and manually annotating farm animal genomes.Mammalian genome : official journal of the International Mammalian Genome Society · 2023
    Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Christine Tait-BurkardThe Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK.
Andrea Doeschl-WilsonThe Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK.
Mike J McGrewThe Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK.
Alan L ArchibaldThe Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK.
Helen M SangThe Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK.
Ross D HoustonThe Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK.
C Bruce WhitelawThe Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK.
Mick WatsonThe Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK. mick.watson@roslin.ed.ac.uk.ORCID 0000-0003-4211-0358
Roslin Institute · GB

Funding

Biotechnology and Biological Sciences Research Council BB/E016812/1Biotechnology and Biological Sciences Research Council BB/P013732/1Biotechnology and Biological Sciences Research Council BB/P013732/1, BB/P013740/1, BB/P013759/1, BB/R004463/1Biotechnology and Biological Sciences Research Council BB/P013740/1Biotechnology and Biological Sciences Research Council BB/P013759/1Biotechnology and Biological Sciences Research Council BB/R004463/1Biotechnology and Biological Sciences Research Council BBS/E/D/05251443Biotechnology and Biological Sciences Research Council BBS/E/D/05251444
6 · The paper itself

Abstract

The human population is growing, and as a result we need to produce more food whilst reducing the impact of farming on the environment. Selective breeding and genomic selection have had a transformational impact on livestock productivity, and now transgenic and genome-editing technologies offer exciting opportunities for the production of fitter, healthier and more-productive livestock. Here, we review recent progress in the application of genome editing to farmed animal species and discuss the potential impact on our ability to produce food.

Indexed as

Gene EditingAnimal HusbandryAnimalsGenomicsLivestock

Identifiers

PMID30477539
PMCPMC6258497
OpenAlexW2902182561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.