ArticleBMC pregnancy and childbirth2018
Pregnancy outcomes following nonobstetric surgery during gestation: a nationwide population-based case-control study in Taiwan.
Article in BMC pregnancy and childbirth, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05759351 (Appendectomy During Pregnancy in General Anesthesia With Perioperative Management Does Not Influence Normal Child Development), which is not on this map. Cited by 14 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Appendectomy During Pregnancy in General Anesthesia With Perioperative Management Does Not Influence Normal Child Development: 10-year Study
Who cites it
14 citing papers in PubMed.
- Appendectomy During Pregnancy and the Risk of Preterm Birth: A Systematic Review of Contemporary Clinical Studies.Journal of clinical medicine · 2026Review
- Review
- Case - Inferior vena caval thrombus associated with a left-sided renal cell carcinoma during pregnancy.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2024Article
- Acute abdomen caused by spontaneous rupture of degenerative hysteromyoma during pregnancy: A case report.World journal of clinical cases · 2023Article
- Risk of adverse fetal outcomes following nonobstetric surgery during gestation: a nationwide population-based analysis.BMC pregnancy and childbirth · 2022Observational
- General anaesthesia for nonobstetric surgery during pregnancy: A narrative review.European journal of anaesthesiology and intensive care · 2022Review
- Pregnancy Outcomes Following Laparoscopic and Open Surgery in Pelvis during Pregnancy: a Nationwide Population-based Study in Korea.Journal of Korean medical science · 2021Article
- Corrective surgery using a gridiron incision for abdominal pain caused by a folded ovary in the third trimester of pregnancy.The Journal of international medical research · 2021Article
- Early Breast Cancers During Pregnancy Treated With Breast-Conserving Surgery in the First Trimester of Gestation: A Feasibility Study.Frontiers in oncology · 2021Article
- Appendectomy, cholecystectomy and diagnostic laparoscopy conducted before pregnancy and risk of adverse birth outcomes: a nationwide registry-based prevalence study 1996-2015.BMC pregnancy and childbirth · 2020Article
- Pancreatic Tumors Complicating Pregnancy: A Concern for Fetomaternal Well Being.International medical case reports journal · 2020Article
- Non-obstetric surgery during pregnancy - an eleven-year retrospective analysis.BMC pregnancy and childbirth · 2019Article
- Obstetric and non-obstetric surgery during pregnancy: A 20-year Danish population-based prevalence study.BMJ open · 2019Article
- Pregnant patients requiring emergency general surgery: a scoping review of diagnostic and management strategies.Canadian journal of surgery. Journal canadien de chirurgieArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhether nonobstetric surgery during gestation is associated with a higher risk of spontaneous abortion or adverse delivery outcomes is still unclear.
methodsWe performed a retrospective case-control study using a Longitudinal Health Insurance Database (LHID 2000) containing claim-data of 1 million randomly selected beneficiaries. We compared the incidences and estimated the adjusted odds ratios (aOR) with 95% confidence interval (95% CI) for spontaneous abortion, adverse delivery outcomes, cesarean delivery, and prolonged hospital stay to determine the risk of adverse outcomes in women who had nonobstetric surgery during gestation as compared to those who did not have any surgery during gestation.
resultsAfter exclusion, we were left with 114,852 delivery and 3999 abortion cases in our study; and 462 (0.39%) of them had nonobstetric surgery under general or regional anesthesia during pregnancy. The leading surgeries were repair of cervical os (33.12%), appendectomy (17.32%), ovarian surgeries (13.64%), and fixation of fractured bone (8.01%).The risk of spontaneous abortion (4.23% vs. 2.43%, aOR:1.53; 95% CI: 1.01-2.31), antepartum hemorrhage (7.14% vs. 2.83%, aOR: 2.51; 95% CI: 1.74-3.61), pre-eclampsia/eclampsia (2.60% vs. 1.01%, aOR: 2.35; 95% CI: 1.30-4.23), gestational diabetes (2.38% vs. 0.69%, aOR: 3.12; 95% CI: 1.69-5.78), prematurity (9.06 vs. 4.90%, aOR: 3.31; 95% CI: 2.54-4.31), cesarean section (43.55% vs. 33.76%, aOR: 1.41; 95% CI: 1.17-1.71), and prolonged hospital stay (1.82% vs. 5.91%, aOR: 3.23; 95% CI: 2.16-4.83) were higher in those women who had nonobstetric surgery after adjusting for age and comorbidities.
conclusionsNonobstetric surgery during gestation were associated with a higher risk of spontaneous abortion, adverse delivery outcomes, cesarean section, and prolonged hospital stay.
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