Evidence map›Paper›PMID 30477430›Full record

ArticleBMC medical research methodology2018

Using the Beta distribution in group-based trajectory models.

Jonathan Elmer, Bobby L Jones, Daniel S Nagin

Abstract read
In one paragraph

Article in BMC medical research methodology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Trial
  2. Trajectory analysis in clinical research.Clinical kidney journal · 2026
    Review
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  16. The Pattern of Hemoglobin A1C Trajectories and Risk of Herpes Zoster Infection: A Follow-Up Study.International journal of environmental research and public health · 2022
    Article
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jonathan ElmerDepartment of Emergency Medicine, Critical Care Medicine and Neurology, University of Pittsburgh, Pittsburgh, PA, USA.
Bobby L JonesUniversity of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Daniel S NaginHeinz College, Carnegie Mellon University, Pittsburgh, PA, 15206, USA. dn03@andrew.cmu.edu.

Funding

Quantitative electroencephalography after cardiac arrestK23NS097629 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ELMER, JONATHAN · 2017 to 2021
$945k
NINDS NIH HHS K23 NS097629
6 · The paper itself

Abstract

backgroundWe demonstrate an application of Group-Based Trajectory Modeling (GBTM) based on the beta distribution. It is offered as an alternative to the normal distribution for modeling continuous longitudinal data that are poorly fit by the normal distribution even with censoring. The primary advantage of the beta distribution is the flexibility of the shape of the density function.

methodsGBTM is a specialized application of finite mixture modeling designed to identify clusters of individuals who follow similar trajectories. Like all finite mixture models, GBTM requires that the distribution of the data composing the mixture be specified. To our knowledge this is the first demonstration of the use of the beta distribution in GBTM. A case study of a beta-based GBTM analyzes data on the neurological activity of comatose cardiac arrest patients.

resultsThe case study shows that the summary measure of neurological activity, the suppression ratio, is not well fit by the normal distribution but due to the flexibility of the shape of the beta density function, the distribution of the suppression ratio by trajectory appears to be well matched by the estimated beta distribution by group.

conclusionsThe addition of the beta distribution to the already available distributional alternatives in software for estimating GBTM is a valuable augmentation to extant distributional alternatives.

Indexed as

AlgorithmsModels, TheoreticalBiomedical ResearchDisease ProgressionHumansNormal DistributionOutcome Assessment, Health CareReproducibility of ResultsStatistical DistributionsBeta distributionCardiac arrestGroup-based trajectory modeling

Identifiers

PMID30477430
PMCPMC6258307

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.