Evidence map›Paper›PMID 30477276›Full record

ArticleNutrients2018

Association between 25-Hydroxyvitamin D Status and Components of Body Composition and Glucose Metabolism in Older Men and Women.

Svea-Vivica Mathieu, Karina Fischer, Bess Dawson-Hughes, Gregor Freystaetter, Felix Beuschlein, Simeon Schietzel, Andreas Egli, Heike A Bischoff-Ferrari

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. There is more to life than serum vitamin D: a lesson from the past.Clinical science (London, England : 1979) · 2022
    Article
  6. Article
  7. Article
  8. Review
  9. Vitamin D and Arterial Hypertension: Facts and Myths.Current hypertension reports · 2020
    Review
  10. Article
  11. Article
  12. Observational
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Svea-Vivica MathieuDepartment of Geriatrics and Aging Research, University Hospital Zurich, 8091 Zurich, Switzerland. svea-vivica.mathieu@uzh.ch.
Karina FischerDepartment of Geriatrics and Aging Research, University Hospital Zurich, 8091 Zurich, Switzerland. karina.fischer@uzh.ch.
Bess Dawson-HughesJean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02153, USA. bess.dawson-hughes@tufts.edu.
Gregor FreystaetterDepartment of Geriatrics and Aging Research, University Hospital Zurich, 8091 Zurich, Switzerland. gregor.freystaetter@usz.ch.
Felix BeuschleinDepartment of Endocrinology, Diabetes, and Clinical Nutrition, University Hospital Zurich, 8091 Zurich, Switzerland. felix.beuschlein@usz.ch.
Simeon SchietzelDepartment of Geriatrics and Aging Research, University Hospital Zurich, 8091 Zurich, Switzerland. simeon.schietzel@usz.ch.
Andreas EgliDepartment of Geriatrics and Aging Research, University Hospital Zurich, 8091 Zurich, Switzerland. andreas.egli@usz.ch.
Heike A Bischoff-FerrariDepartment of Geriatrics and Aging Research, University Hospital Zurich, 8091 Zurich, Switzerland. heike.bischoff@usz.ch.
Stadtspital Waid · CHTufts University · USUniversity Hospital of Zurich · CH

Funding

Baugarten Foundation Centre Grant to the Centre on Aging and Mobility at the University of Zurich and University Hospital ZurichSwiss National Foundation Professorship PP00B-114864
6 · The paper itself

Abstract

Obesity and sarcopenia are major causes of morbidity and mortality among seniors. Vitamin D deficiency is very common especially among seniors and has been associated with both muscle health and obesity. This study investigated if 25-hydroxyvitamin D (25(OH)D) status is associated with body composition and insulin resistance using baseline data of a completed RCT among relatively healthy community-dwelling seniors (271 seniors age 60+ years undergoing elective surgery for unilateral total knee replacement due to osteoarthritis). Cross-sectional analysis compared appendicular lean mass index (ALMI: lean mass kg/height m²) and fat mass index (FMI: fat mass kg/height m²) assessed by DXA and insulin resistance between quartiles of serum 25(OH)D concentration using multivariable linear regression adjusted for age, sex, smoking status, physical activity, and body mass index (BMI). Participants in the lowest serum 25(OH)D quartile (4.7⁻17.5 ng/mL) had a higher fat mass (9.3 kg/m²) compared with participants in the third (8.40 kg/m²; Q3 = 26.1⁻34.8 ng/mL) and highest (8.37 kg/m²; Q4 = 34.9⁻62.5 ng/mL) quartile (

Indexed as

Body CompositionBody Mass IndexInsulin ResistanceAdipose TissueAgedBlood GlucoseBody Fluid CompartmentsCross-Sectional StudiesHumansInsulin-Secreting CellsMaleMiddle AgedMusclesObesitySarcopeniaVitamin D25-hydroxyvitamin DBlood GlucoseVitamin Dageingbody compositiondiabeteselderlyinsulin resistancemetabolic syndromevitamin D

Identifiers

PMID30477276
PMCPMC6315833
OpenAlexW2902305815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.