Evidence map›Paper›PMID 30477270›Full record

ArticleNanomaterials (Basel, Switzerland)2018

Elastomeric Polyurethane Foams Incorporated with Nanosized Hydroxyapatite Fillers for Plastic Reconstruction.

Lili Lin, Jingqi Ma, Quanjing Mei, Bin Cai, Jie Chen, Yi Zuo, Qin Zou, Jidong Li, Yubao Li

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Lili LinResearch Center for Nano-Biomaterials, Analytical and Testing Center, Sichuan University, Chengdu 610064, China. linll900730@163.com.
Jingqi MaResearch Center for Nano-Biomaterials, Analytical and Testing Center, Sichuan University, Chengdu 610064, China. jingqima2018@gmail.com.
Quanjing MeiResearch Center for Nano-Biomaterials, Analytical and Testing Center, Sichuan University, Chengdu 610064, China. scumqj@foxmail.com.
Bin CaiResearch Center for Nano-Biomaterials, Analytical and Testing Center, Sichuan University, Chengdu 610064, China. haisengyan@sina.com.
Jie ChenResearch Center for Nano-Biomaterials, Analytical and Testing Center, Sichuan University, Chengdu 610064, China. ChenJie005@outlook.com.
Yi ZuoResearch Center for Nano-Biomaterials, Analytical and Testing Center, Sichuan University, Chengdu 610064, China. zoae@scu.edu.cn.ORCID 0000-0003-2301-9786
Qin ZouResearch Center for Nano-Biomaterials, Analytical and Testing Center, Sichuan University, Chengdu 610064, China. zouqin80913@126.com.
Jidong LiResearch Center for Nano-Biomaterials, Analytical and Testing Center, Sichuan University, Chengdu 610064, China. nic1979@scu.edu.cn.
Yubao LiResearch Center for Nano-Biomaterials, Analytical and Testing Center, Sichuan University, Chengdu 610064, China. nic7504@scu.edu.cn.
Sichuan University · CN

Funding

China NSFC fund No. 31670965National Key Research and Development Program of China No. 2017YFC1104300/ 2017YFC1104303
6 · The paper itself

Abstract

Plastic surgeons have long searched for the ideal materials to use in craniomaxillofacial reconstruction. The aim of this study was to obtain a novel porous elastomer based on designed aliphatic polyurethane (PU) and nanosized hydroxyapatite (n-HA) fillers for plastic reconstruction. The physicochemical properties of the prepared composite elastomer were characterized by infrared spectroscopy (IR), X-ray diffraction (XRD), scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM-EDX), transmission electron microscopy (TEM), thermal analysis, mechanical tests, and X-ray photoelectron spectroscopy (XPS). The results assessed by the dynamic mechanical analysis (DMA) demonstrated that the n-HA/PU compounded foams had a good elasticity, flexibility, and supporting strength. The homogenous dispersion of the n-HA fillers could be observed throughout the cross-linked PU matrix. The porous elastomer also showed a uniform pore structure and a resilience to hold against general press and tensile stress. In addition, the elastomeric foams showed no evidence of cytotoxicity and exhibited the ability to enhance cell proliferation and attachment when evaluated using rat-bone-marrow-derived mesenchymal stem cells (BMSCs). The animal experiments indicated that the porous elastomers could form a good integration with bone tissue. The presence of n-HA fillers promoted cell infiltration and tissue regeneration. The elastomeric and bioactive n-HA/PU composite foam could be a good candidate for future plastic reconstruction.

Indexed as

biocompatibilityelastomeric foamhydroxyapatite/polyurethanenanosized dispersionplastic reconstructionviscoelasticity

Identifiers

PMID30477270
PMCPMC6316613
OpenAlexW2902681304

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.