Evidence map›Paper›PMID 30477265›Full record

ArticleNanomaterials (Basel, Switzerland)2018

Electrospun Alginate Fibers: Mixing of Two Different Poly(ethylene oxide) Grades to Improve Fiber Functional Properties.

Barbara Vigani, Silvia Rossi, Giulia Milanesi, Maria Cristina Bonferoni, Giuseppina Sandri, Giovanna Bruni, Franca Ferrari

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Barbara ViganiDepartment of Drug Sciences, University of Pavia, 27100 Pavia, Italy. barbara.vigani@unipv.it.
Silvia RossiDepartment of Drug Sciences, University of Pavia, 27100 Pavia, Italy. silvia.rossi@unipv.it.ORCID 0000-0001-9511-3857
Giulia MilanesiDepartment of Drug Sciences, University of Pavia, 27100 Pavia, Italy. giulia.milanesi02@universitadipavia.it.
Maria Cristina BonferoniDepartment of Drug Sciences, University of Pavia, 27100 Pavia, Italy. cbonferoni@unipv.it.ORCID 0000-0002-1194-9372
Giuseppina SandriDepartment of Drug Sciences, University of Pavia, 27100 Pavia, Italy. giuseppina.sandri@unipv.it.ORCID 0000-0001-6766-9321
Giovanna BruniDepartment of Chemistry, University of Pavia, 27100 Pavia, Italy. giovanna.bruni@unipv.it.ORCID 0000-0003-1958-2998
Franca FerrariDepartment of Drug Sciences, University of Pavia, 27100 Pavia, Italy. franca.ferrari@unipv.it.
University of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present work was to investigate how the molecular weight (MW) of poly(ethylene oxide) (PEO), a synthetic polymer able to improve alginate (ALG) electrospinnability, could affect ALG-based fiber morphology and mechanical properties. Two PEO grades, having different MWs (high, h-PEO, and low, l-PEO) were blended with ALG: the concentrations of both PEOs in each mixture were defined so that each h-PEO/l-PEO combination would show the same viscosity at high shear rate. Seven ALG/h-PEO/l-PEO mixtures were prepared and characterized in terms of viscoelasticity and conductivity and, for each mixture, a complex parameter rH/rL was calculated to better identify which of the two PEO grades prevails over the other in terms of exceeding the critical entanglement concentration. Thereafter, each mixture was electrospun by varying the process parameters; the fiber morphology and mechanical properties were evaluated. Finally, viscoelastic measurements were performed to verify the formation of intermolecular hydrogen bonds between the two PEO grades and ALG. rH/rL has been proved to be the parameter that better explains the effect of the electrospinning conditions on fiber dimension. The addition of a small amount of h-PEO to l-PEO was responsible for a significant increase in fiber mechanical resistance, without affecting the nano-scale fiber size. Moreover, the mixing of h-PEO and l-PEO improved the interaction with ALG, resulting in an increase in chain entanglement degree that is functional in the electrospinning process.

Indexed as

ALG-containing fiberscritical entanglement concentrationelectrospinningintermolecular hydrogen bondsmechanical propertiesmolecular weightpoly(ethylene oxide)

Identifiers

PMID30477265
PMCPMC6315736
OpenAlexW2902071425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.